Association between calcium/magnesium ratio and insulin resistance in women with obesity and normal-weight women

ABSTRACT The aim of this study was to evaluate the association between the calcium/magnesium (Ca/Mg) ratio and insulin resistance in women with obesity and normal-weight women. This was a cross-sectional study with 128 women (62 women with obesity and 66 normal-weight women). We measured dietary min...

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Veröffentlicht in:Revista chilena de nutrición 2021-10, Vol.48 (5), p.758-767
Hauptverfasser: Clímaco-Cruz, Kyria Jayanne, Oliveira, Ana Raquel Soares de, Silva-Morais, Jennifer Beatriz, Melo, Stéfany Rodrigues de Sousa, Santos, Loanne Rocha dos, Fontenelle, Larissa Cristina, Freitas, Suelem Torres de, Silva, Vladimir Costa, Nery-Costa, Carlos Henrique, Simeone-Henriques, Gilberto, Matos Neto, Emídio Marques de, Marreiro, Dilina do Nascimento
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container_issue 5
container_start_page 758
container_title Revista chilena de nutrición
container_volume 48
creator Clímaco-Cruz, Kyria Jayanne
Oliveira, Ana Raquel Soares de
Silva-Morais, Jennifer Beatriz
Melo, Stéfany Rodrigues de Sousa
Santos, Loanne Rocha dos
Fontenelle, Larissa Cristina
Freitas, Suelem Torres de
Silva, Vladimir Costa
Nery-Costa, Carlos Henrique
Simeone-Henriques, Gilberto
Matos Neto, Emídio Marques de
Marreiro, Dilina do Nascimento
description ABSTRACT The aim of this study was to evaluate the association between the calcium/magnesium (Ca/Mg) ratio and insulin resistance in women with obesity and normal-weight women. This was a cross-sectional study with 128 women (62 women with obesity and 66 normal-weight women). We measured dietary minerals intake and analyzed magnesium and calcium biomarkers. Ca/Mg ratio in diet, plasma and urine were calculated. We have evaluated glycemic parameters. Women with obesity had low dietary magnesium, reduced plasma and erythrocyte magnesium concentrations, and elevated urinary magnesium excretion. Plasma calcium concentration was lower and urinary calcium excretion was higher in patients with obesity than in the normal-weight group. Dietary magnesium and calcium intake per kilogram of body weight per day was lower in obese women than in the control group. Ca/Mg ratio in plasma and urine were elevated in women with obesity. We found a significant correlation among magnesium biomarkers and calcium parameters. Ca/Mg ratio seems to be associated with insulin resistance in obese women.
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title Association between calcium/magnesium ratio and insulin resistance in women with obesity and normal-weight women
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