Case report: First reported case of spondylodiscitis caused by Gemella morbillorum in South Africa
Pyogenic spondylodiscitis is an uncommon but important clinical condition that often requires medical and/or surgical management. We report a case of spondylodiscitis caused by a rare pathogen, Gemella morbillorum. To date, worldwide, only six such cases of confirmed spondylodiscitis infection with...
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| Veröffentlicht in: | SAMJ: South African Medical Journal 2024-11, Vol.114 (11), p.e2022-30 |
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| creator | Pillay, J Van der Linden, N M |
| description | Pyogenic spondylodiscitis is an uncommon but important clinical condition that often requires medical and/or surgical management. We report a case of spondylodiscitis caused by a rare pathogen, Gemella morbillorum. To date, worldwide, only six such cases of confirmed spondylodiscitis infection with this rare pathogen have been documented, and this is the first reported case in South Africa. The patient was a 55-year-old female who presented to us with a 1-month history of severe back pain radiating to her left leg. She reported to us that she visited the dentist around the time of onset of the symptoms. A workup showed raised inflammatory markers, and a positron emission tomography scan indicated features of discitis at level L2/L3. Tissue cultures from a biopsy identified G. morbillorum species infection, and she was treated successfully with antibiotics for 6 weeks. It is important to have a high index of suspicion when a patient has a history of dental work, and to rule out associated infection such as endocarditis. Treatment with culture-driven antibiotics yields good results. |
| doi_str_mv | 10.7196/SAMJ.2024.v114i11.2022 |
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We report a case of spondylodiscitis caused by a rare pathogen, Gemella morbillorum. To date, worldwide, only six such cases of confirmed spondylodiscitis infection with this rare pathogen have been documented, and this is the first reported case in South Africa. The patient was a 55-year-old female who presented to us with a 1-month history of severe back pain radiating to her left leg. She reported to us that she visited the dentist around the time of onset of the symptoms. A workup showed raised inflammatory markers, and a positron emission tomography scan indicated features of discitis at level L2/L3. Tissue cultures from a biopsy identified G. morbillorum species infection, and she was treated successfully with antibiotics for 6 weeks. It is important to have a high index of suspicion when a patient has a history of dental work, and to rule out associated infection such as endocarditis. 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We report a case of spondylodiscitis caused by a rare pathogen, Gemella morbillorum. To date, worldwide, only six such cases of confirmed spondylodiscitis infection with this rare pathogen have been documented, and this is the first reported case in South Africa. The patient was a 55-year-old female who presented to us with a 1-month history of severe back pain radiating to her left leg. She reported to us that she visited the dentist around the time of onset of the symptoms. A workup showed raised inflammatory markers, and a positron emission tomography scan indicated features of discitis at level L2/L3. Tissue cultures from a biopsy identified G. morbillorum species infection, and she was treated successfully with antibiotics for 6 weeks. It is important to have a high index of suspicion when a patient has a history of dental work, and to rule out associated infection such as endocarditis. Treatment with culture-driven antibiotics yields good results.</description><subject>Anti-Bacterial Agents - therapeutic use</subject><subject>Backache</subject><subject>Complications and side effects</subject><subject>Diagnosis</subject><subject>Discitis - diagnosis</subject><subject>Discitis - drug therapy</subject><subject>Discitis - microbiology</subject><subject>Drug therapy</subject><subject>Female</subject><subject>Gemella - isolation & purification</subject><subject>Gram-Positive Bacterial Infections - diagnosis</subject><subject>Gram-Positive Bacterial Infections - drug therapy</subject><subject>Gram-Positive Bacterial Infections - microbiology</subject><subject>Health aspects</subject><subject>Health Care Sciences & Services</subject><subject>Health Policy & Services</subject><subject>Humans</subject><subject>Infection</subject><subject>Inflammation</subject><subject>Intervertebral disk</subject><subject>Lumbar Vertebrae - microbiology</subject><subject>Magnetic Resonance Imaging</subject><subject>Medical Ethics</subject><subject>Medicine, General & Internal</subject><subject>Medicine, Legal</subject><subject>Medicine, Research & Experimental</subject><subject>Middle Aged</subject><subject>PET imaging</subject><subject>South Africa</subject><subject>Staphylococcal infections</subject><issn>0256-9574</issn><issn>2078-5135</issn><issn>2078-5135</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkU2LFDEQhoMo7rDuX1gCgnjp2Xx20t6GwV2VFQ-j55BOV-9E0p0x6Rbm35tmRnRuSyChUs9bqXqD0C0la0Wb-m63-fplzQgT69-UCk_pErAXaMWI0pWkXL5EK8JkXTVSiSt0k7NvC6GUFI14ja54I6lQQqxQu7UZcIJDTNMHfO9Tns4RdNgtudjjfIhjdwyx89n5yeeSmHPJt0f8AAOEYPEQU-tDiGkesB_xLs7THm_65J19g171NmS4OZ_X6Mf9x-_bT9Xjt4fP281j9cQpnSrdMtY54LqTrnVacanLVK2rndKk5lxJVzd17UADBUpVz6xTru0UECsZ4fwarU91S5MQovkZ5zSWB81uscIsViyeEUIZKRspgvcnwSHFXzPkyQxlwGWcEeKcDadMc8ZpMfR5KNVcFfTtCX2yAYwf-zgl6xbcbDSVsuGKiX_NXlBldTB4F0fofbm_ELz7T7AHG6Z9jmGefBzzJXh7bnVuB-jMIfnBpqP5--f8D3Pyq1U</recordid><startdate>20241101</startdate><enddate>20241101</enddate><creator>Pillay, J</creator><creator>Van der Linden, N M</creator><general>Health & Medical Publishing Group</general><general>South African Medical Association</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope><scope>GPN</scope></search><sort><creationdate>20241101</creationdate><title>Case report: First reported case of spondylodiscitis caused by Gemella morbillorum in South Africa</title><author>Pillay, J ; Van der Linden, N M</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-g311t-8b22dce38d5cbc87358202bc6c78063375c6966ce8e1e117f2ac7cbd7e0a52033</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2024</creationdate><topic>Anti-Bacterial Agents - therapeutic use</topic><topic>Backache</topic><topic>Complications and side effects</topic><topic>Diagnosis</topic><topic>Discitis - diagnosis</topic><topic>Discitis - drug therapy</topic><topic>Discitis - microbiology</topic><topic>Drug therapy</topic><topic>Female</topic><topic>Gemella - isolation & purification</topic><topic>Gram-Positive Bacterial Infections - diagnosis</topic><topic>Gram-Positive Bacterial Infections - drug therapy</topic><topic>Gram-Positive Bacterial Infections - microbiology</topic><topic>Health aspects</topic><topic>Health Care Sciences & Services</topic><topic>Health Policy & Services</topic><topic>Humans</topic><topic>Infection</topic><topic>Inflammation</topic><topic>Intervertebral disk</topic><topic>Lumbar Vertebrae - microbiology</topic><topic>Magnetic Resonance Imaging</topic><topic>Medical Ethics</topic><topic>Medicine, General & Internal</topic><topic>Medicine, Legal</topic><topic>Medicine, Research & Experimental</topic><topic>Middle Aged</topic><topic>PET imaging</topic><topic>South Africa</topic><topic>Staphylococcal infections</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Pillay, J</creatorcontrib><creatorcontrib>Van der Linden, N M</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><collection>SciELO</collection><jtitle>SAMJ: South African Medical Journal</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Pillay, J</au><au>Van der Linden, N M</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Case report: First reported case of spondylodiscitis caused by Gemella morbillorum in South Africa</atitle><jtitle>SAMJ: South African Medical Journal</jtitle><addtitle>S Afr Med J</addtitle><date>2024-11-01</date><risdate>2024</risdate><volume>114</volume><issue>11</issue><spage>e2022</spage><epage>30</epage><pages>e2022-30</pages><issn>0256-9574</issn><issn>2078-5135</issn><eissn>2078-5135</eissn><abstract>Pyogenic spondylodiscitis is an uncommon but important clinical condition that often requires medical and/or surgical management. We report a case of spondylodiscitis caused by a rare pathogen, Gemella morbillorum. To date, worldwide, only six such cases of confirmed spondylodiscitis infection with this rare pathogen have been documented, and this is the first reported case in South Africa. The patient was a 55-year-old female who presented to us with a 1-month history of severe back pain radiating to her left leg. She reported to us that she visited the dentist around the time of onset of the symptoms. A workup showed raised inflammatory markers, and a positron emission tomography scan indicated features of discitis at level L2/L3. Tissue cultures from a biopsy identified G. morbillorum species infection, and she was treated successfully with antibiotics for 6 weeks. It is important to have a high index of suspicion when a patient has a history of dental work, and to rule out associated infection such as endocarditis. Treatment with culture-driven antibiotics yields good results.</abstract><cop>South Africa</cop><pub>Health & Medical Publishing Group</pub><pmid>39514744</pmid><doi>10.7196/SAMJ.2024.v114i11.2022</doi><tpages>3</tpages><oa>free_for_read</oa></addata></record> |
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| subjects | Anti-Bacterial Agents - therapeutic use Backache Complications and side effects Diagnosis Discitis - diagnosis Discitis - drug therapy Discitis - microbiology Drug therapy Female Gemella - isolation & purification Gram-Positive Bacterial Infections - diagnosis Gram-Positive Bacterial Infections - drug therapy Gram-Positive Bacterial Infections - microbiology Health aspects Health Care Sciences & Services Health Policy & Services Humans Infection Inflammation Intervertebral disk Lumbar Vertebrae - microbiology Magnetic Resonance Imaging Medical Ethics Medicine, General & Internal Medicine, Legal Medicine, Research & Experimental Middle Aged PET imaging South Africa Staphylococcal infections |
| title | Case report: First reported case of spondylodiscitis caused by Gemella morbillorum in South Africa |
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