Virtual Screening for the Selection of New Candidates to Trypanosoma cruzi Farnesyl Pyrophosphate Synthase Inhibitors

Chagas disease is a tropical parasitic disease that is caused by Trypanosoma cruzi and causes 12,000 deaths per year, mainly in Latin America. The available drugs for treating have severe limitations, including poor efficacy and high toxicity. One way to overcome these limitations is targeting prior...

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Veröffentlicht in:	Journal of the Brazilian Chemical Society 2018-12, Vol.29 (12), p.2554-2568
Hauptverfasser:	Oliveira, Larissa, Araújo, Janay, Costa Júnior, David, dos Santos Junior, Manoelito, Santos Júnior, Aníbal, Leite, Franco
Format:	Artikel
Sprache:	eng
Schlagworte:	CHEMISTRY, MULTIDISCIPLINARY
Online-Zugang:	Volltext
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