The Role of the Conformational Dynamics of Glutathione S-Transferase Epsilon Class on Insecticide Resistance in Anopheles gambiae

Glutathione S-transferases (GSTs) are enzymes capable of metabolizing cytotoxic compounds. The enzyme AgGSTE2, member of epsilon class GSTs (GSTE), is the most important GST conferring resistance to dichloro-diphenyl-trichloroethane (DDT) in Anopheles gambiae. We have investigated the conformational...

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Veröffentlicht in:	Journal of the Brazilian Chemical Society 2016-09, Vol.27 (9), p.1602-1615
Hauptverfasser:	Pontes, Frederico J. S., Maia, Rafael T., Lima, Maria Carolina P., Ayres, Constância F. J., Soares, Thereza A.
Format:	Artikel
Sprache:	eng
Schlagworte:	CHEMISTRY, MULTIDISCIPLINARY
Online-Zugang:	Volltext
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