Novel chiral ionic liquid (CIL) assisted selectivity enhancement to (L)-proline catalyzed asymmetric aldol reactions

Novel chiral ionic liquid (CIL) assisted selectivity enhancement to (L)-proline catalyzed asymmetric aldol reactions

A significant improvement of the chemical yields (up to 88%), stereoselectivity (> 99:1) and enantiomeric excesses (up to 98%) of (L)-proline catalyzed direct asymmetric aldol reaction was found when proline based chiral ionic liquids (CILs) were added as additives. Different ratios of DMSO/H2O a...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Journal of the Brazilian Chemical Society 2011-09, Vol.22 (9), p.1736-1741
Hauptverfasser: Zhang, Long, Zhang, Haibo, Luo, Huadong, Zhou, Xiaohai, Cheng, Gongzhen
Format: Artikel
Sprache:eng
Schlagworte:
CHEMISTRY, MULTIDISCIPLINARY
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:A significant improvement of the chemical yields (up to 88%), stereoselectivity (> 99:1) and enantiomeric excesses (up to 98%) of (L)-proline catalyzed direct asymmetric aldol reaction was found when proline based chiral ionic liquids (CILs) were added as additives. Different ratios of DMSO/H2O as solvent and chiral ionic liquids (CILs) with chiral cations of different chain length were investigated
ISSN:0103-5053
1678-4790
DOI:10.1590/S0103-50532011000900016