Descriptor-and fragment-based QSAR models for a series of Schistosoma mansoni purine nucleoside inhibitors

The enzyme purine nucleoside phosphorylase from Schistosoma mansoni (SmPNP) is an attractive molecular target for the treatment of major parasitic infectious diseases, with special emphasis on its role in the discovery of new drugs against schistosomiasis, a tropical disease that affects millions of...

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Veröffentlicht in:	Journal of the Brazilian Chemical Society 2011-09, Vol.22 (9), p.1718-1726
Hauptverfasser:	Freitas, Humberto F, Postigo, Matheus P, Andricopulo, Adriano D, Castilho, Marcelo S
Format:	Artikel
Sprache:	eng
Schlagworte:	CHEMISTRY, MULTIDISCIPLINARY
Online-Zugang:	Volltext
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