Effectiveness of antiemetics in control of antineoplastic chemotherapy-induced emesis at home
Objective Evaluating if antiemetics are effective in the prevention or treatment at home, of chemotherapy-induced emesis. Methods In total, were included 42 women with breast cancer in moderately emetogenic chemotherapy, using dexamethasone/ondansetron before each cycle. The frequency of nausea and...
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description | Objective Evaluating if antiemetics are effective in the prevention or treatment at home, of chemotherapy-induced emesis. Methods In total, were included 42 women with breast cancer in moderately emetogenic chemotherapy, using dexamethasone/ondansetron before each cycle. The frequency of nausea and vomiting was obtained by applying the instrument in the pre-chemotherapy period, and 24h, 48h, 72h and 96h after chemotherapy. The use of antiemetics was considered in accordance with adherence to medical prescription. Results All patients (n = 42, 100%) reported emesis at some point. Only five cases (11.9%) were anticipatory. In the first 24 hours (acute emesis), 38 (90.5%)ayed), emesis was reported by all despite the regular use (n = 20, 47.6%) or not (n = 22, 52.4%) of antiemetics (ondansetron, dexamethasone and metoclopramide/or dimenhydrinate). Conclusion Antiemetics were not effective in the prevention or treatment at home, of chemotherapy-induced emesis.
Objetivo : Avaliar se antieméticos são eficazes na prevenção ou tratamento da emese induzida pela quimioterapia antineoplásica, em domicílio. Métodos : Foram incluídas 42 mulheres com câncer de mama, em quimioterapia moderadamente emetogênica, submetidas à dexametasona/ondansetrona antes de cada ciclo. A frequência de náuseas e vômitos foi obtida por instrumento aplicado nos tempos pré-quimioterapia e 24h, 48h, 72h e 96h pós-quimioterapia. O uso de antieméticos foi considerado conforme adesão à prescrição médica. Resultados : Todas as pacientes (n=42, 100%) relataram emese em algum momento. Apenas cinco casos (11,9%) foram antecipatórios. Nas primeiras 24h (emese aguda), 38 (90,5%) apresentaram náuseas associadas (n=20, 47,6%) ou não (n=18, 42,8%) a vômitos e, após este período (tardio), a emese foi referida por todas, apesar da utilização regular (n=20, 47,6%) ou não (n=22, 52,4%) de antieméticos (ondansetrona, dexametasona, metoclopramida e/ou dimenidrinato). Conclusão : Os antieméticos não foram eficazes na prevenção ou no tratamento da emese induzida pela quimioterapia, em domicílio. |
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Objetivo : Avaliar se antieméticos são eficazes na prevenção ou tratamento da emese induzida pela quimioterapia antineoplásica, em domicílio. Métodos : Foram incluídas 42 mulheres com câncer de mama, em quimioterapia moderadamente emetogênica, submetidas à dexametasona/ondansetrona antes de cada ciclo. A frequência de náuseas e vômitos foi obtida por instrumento aplicado nos tempos pré-quimioterapia e 24h, 48h, 72h e 96h pós-quimioterapia. O uso de antieméticos foi considerado conforme adesão à prescrição médica. Resultados : Todas as pacientes (n=42, 100%) relataram emese em algum momento. Apenas cinco casos (11,9%) foram antecipatórios. Nas primeiras 24h (emese aguda), 38 (90,5%) apresentaram náuseas associadas (n=20, 47,6%) ou não (n=18, 42,8%) a vômitos e, após este período (tardio), a emese foi referida por todas, apesar da utilização regular (n=20, 47,6%) ou não (n=22, 52,4%) de antieméticos (ondansetrona, dexametasona, metoclopramida e/ou dimenidrinato). Conclusão : Os antieméticos não foram eficazes na prevenção ou no tratamento da emese induzida pela quimioterapia, em domicílio.</description><identifier>ISSN: 0103-2100</identifier><identifier>ISSN: 1982-0194</identifier><identifier>EISSN: 0103-2100</identifier><identifier>DOI: 10.1590/1982-0194201400069</identifier><language>eng</language><publisher>Escola Paulista de Enfermagem, Universidade Federal de São Paulo</publisher><subject>NURSING</subject><ispartof>Acta paulista de enfermagem, 2014-10, Vol.27 (5), p.412-418</ispartof><rights>This work is licensed under a Creative Commons Attribution-NonCommercial 3.0 International License.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c260t-6431930d9046caed004a4d67afd0db4dcf99dfd1dbe7bbe655d7f62663aa4ed93</citedby><cites>FETCH-LOGICAL-c260t-6431930d9046caed004a4d67afd0db4dcf99dfd1dbe7bbe655d7f62663aa4ed93</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>230,315,781,785,865,886,27929,27930</link.rule.ids></links><search><creatorcontrib>Castro, Marielly Cunha</creatorcontrib><creatorcontrib>Araújo, Suely Amorim de</creatorcontrib><creatorcontrib>Mendes, Thaís Rezende</creatorcontrib><creatorcontrib>Vilarinho, Glauciane Silva</creatorcontrib><creatorcontrib>Mendonça, Maria Angélica Oliveira</creatorcontrib><title>Effectiveness of antiemetics in control of antineoplastic chemotherapy-induced emesis at home</title><title>Acta paulista de enfermagem</title><addtitle>Acta paul. enferm</addtitle><description>Objective Evaluating if antiemetics are effective in the prevention or treatment at home, of chemotherapy-induced emesis. Methods In total, were included 42 women with breast cancer in moderately emetogenic chemotherapy, using dexamethasone/ondansetron before each cycle. The frequency of nausea and vomiting was obtained by applying the instrument in the pre-chemotherapy period, and 24h, 48h, 72h and 96h after chemotherapy. The use of antiemetics was considered in accordance with adherence to medical prescription. Results All patients (n = 42, 100%) reported emesis at some point. Only five cases (11.9%) were anticipatory. In the first 24 hours (acute emesis), 38 (90.5%)ayed), emesis was reported by all despite the regular use (n = 20, 47.6%) or not (n = 22, 52.4%) of antiemetics (ondansetron, dexamethasone and metoclopramide/or dimenhydrinate). Conclusion Antiemetics were not effective in the prevention or treatment at home, of chemotherapy-induced emesis.
Objetivo : Avaliar se antieméticos são eficazes na prevenção ou tratamento da emese induzida pela quimioterapia antineoplásica, em domicílio. Métodos : Foram incluídas 42 mulheres com câncer de mama, em quimioterapia moderadamente emetogênica, submetidas à dexametasona/ondansetrona antes de cada ciclo. A frequência de náuseas e vômitos foi obtida por instrumento aplicado nos tempos pré-quimioterapia e 24h, 48h, 72h e 96h pós-quimioterapia. O uso de antieméticos foi considerado conforme adesão à prescrição médica. Resultados : Todas as pacientes (n=42, 100%) relataram emese em algum momento. Apenas cinco casos (11,9%) foram antecipatórios. Nas primeiras 24h (emese aguda), 38 (90,5%) apresentaram náuseas associadas (n=20, 47,6%) ou não (n=18, 42,8%) a vômitos e, após este período (tardio), a emese foi referida por todas, apesar da utilização regular (n=20, 47,6%) ou não (n=22, 52,4%) de antieméticos (ondansetrona, dexametasona, metoclopramida e/ou dimenidrinato). Conclusão : Os antieméticos não foram eficazes na prevenção ou no tratamento da emese induzida pela quimioterapia, em domicílio.</description><subject>NURSING</subject><issn>0103-2100</issn><issn>1982-0194</issn><issn>0103-2100</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><recordid>eNpVkEFLAzEQhYMoWKt_wFP-wNbJbjZrjlKqFgoe1KOEbDKhKbubkqRC_727tIJe5g083gzvI-SewYLVEh6YfCwLYJKXwDgACHlBZsCgKkoGcPlnvyY3Ke0A6qYBmJGvlXNosv_GAVOiwVE9ZI89Zm8S9QM1YcgxdL_OgGHf6TS61GyxD3mLUe-PhR_swaClYzL5RHWm29DjLblyukt4d9Y5-XxefSxfi83by3r5tClMKSAXgldMVmAlcGE0WgCuuRWNdhZsy61xUlpnmW2xaVsUdW0bJ0ohKq05WlnNyeJ0NxmPXVC7cIjD-FC9T73V1PsMpoZpjIHyFDAxpBTRqX30vY5HxUBNRNVEVP0jWv0ArMFomA</recordid><startdate>20141001</startdate><enddate>20141001</enddate><creator>Castro, Marielly Cunha</creator><creator>Araújo, Suely Amorim de</creator><creator>Mendes, Thaís Rezende</creator><creator>Vilarinho, Glauciane Silva</creator><creator>Mendonça, Maria Angélica Oliveira</creator><general>Escola Paulista de Enfermagem, Universidade Federal de São Paulo</general><scope>AAYXX</scope><scope>CITATION</scope><scope>GPN</scope></search><sort><creationdate>20141001</creationdate><title>Effectiveness of antiemetics in control of antineoplastic chemotherapy-induced emesis at home</title><author>Castro, Marielly Cunha ; Araújo, Suely Amorim de ; Mendes, Thaís Rezende ; Vilarinho, Glauciane Silva ; Mendonça, Maria Angélica Oliveira</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c260t-6431930d9046caed004a4d67afd0db4dcf99dfd1dbe7bbe655d7f62663aa4ed93</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><topic>NURSING</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Castro, Marielly Cunha</creatorcontrib><creatorcontrib>Araújo, Suely Amorim de</creatorcontrib><creatorcontrib>Mendes, Thaís Rezende</creatorcontrib><creatorcontrib>Vilarinho, Glauciane Silva</creatorcontrib><creatorcontrib>Mendonça, Maria Angélica Oliveira</creatorcontrib><collection>CrossRef</collection><collection>SciELO</collection><jtitle>Acta paulista de enfermagem</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Castro, Marielly Cunha</au><au>Araújo, Suely Amorim de</au><au>Mendes, Thaís Rezende</au><au>Vilarinho, Glauciane Silva</au><au>Mendonça, Maria Angélica Oliveira</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Effectiveness of antiemetics in control of antineoplastic chemotherapy-induced emesis at home</atitle><jtitle>Acta paulista de enfermagem</jtitle><addtitle>Acta paul. enferm</addtitle><date>2014-10-01</date><risdate>2014</risdate><volume>27</volume><issue>5</issue><spage>412</spage><epage>418</epage><pages>412-418</pages><issn>0103-2100</issn><issn>1982-0194</issn><eissn>0103-2100</eissn><abstract>Objective Evaluating if antiemetics are effective in the prevention or treatment at home, of chemotherapy-induced emesis. Methods In total, were included 42 women with breast cancer in moderately emetogenic chemotherapy, using dexamethasone/ondansetron before each cycle. The frequency of nausea and vomiting was obtained by applying the instrument in the pre-chemotherapy period, and 24h, 48h, 72h and 96h after chemotherapy. The use of antiemetics was considered in accordance with adherence to medical prescription. Results All patients (n = 42, 100%) reported emesis at some point. Only five cases (11.9%) were anticipatory. In the first 24 hours (acute emesis), 38 (90.5%)ayed), emesis was reported by all despite the regular use (n = 20, 47.6%) or not (n = 22, 52.4%) of antiemetics (ondansetron, dexamethasone and metoclopramide/or dimenhydrinate). Conclusion Antiemetics were not effective in the prevention or treatment at home, of chemotherapy-induced emesis.
Objetivo : Avaliar se antieméticos são eficazes na prevenção ou tratamento da emese induzida pela quimioterapia antineoplásica, em domicílio. Métodos : Foram incluídas 42 mulheres com câncer de mama, em quimioterapia moderadamente emetogênica, submetidas à dexametasona/ondansetrona antes de cada ciclo. A frequência de náuseas e vômitos foi obtida por instrumento aplicado nos tempos pré-quimioterapia e 24h, 48h, 72h e 96h pós-quimioterapia. O uso de antieméticos foi considerado conforme adesão à prescrição médica. Resultados : Todas as pacientes (n=42, 100%) relataram emese em algum momento. Apenas cinco casos (11,9%) foram antecipatórios. Nas primeiras 24h (emese aguda), 38 (90,5%) apresentaram náuseas associadas (n=20, 47,6%) ou não (n=18, 42,8%) a vômitos e, após este período (tardio), a emese foi referida por todas, apesar da utilização regular (n=20, 47,6%) ou não (n=22, 52,4%) de antieméticos (ondansetrona, dexametasona, metoclopramida e/ou dimenidrinato). Conclusão : Os antieméticos não foram eficazes na prevenção ou no tratamento da emese induzida pela quimioterapia, em domicílio.</abstract><pub>Escola Paulista de Enfermagem, Universidade Federal de São Paulo</pub><doi>10.1590/1982-0194201400069</doi><tpages>7</tpages><oa>free_for_read</oa></addata></record> |
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title | Effectiveness of antiemetics in control of antineoplastic chemotherapy-induced emesis at home |
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