C-Reactive Protein to Albumin Ratio as A Novel Inflammatory-Based Marker for 30-Day Mortality in Patients Undergoing Transcatheter Aortic Valve Replacement
Abstract Objective: We aimed to investigate whether C-reactive protein to albumin ratio (CAR) predicts the early and late mortality in patients undergoing transcatheter aortic valve replacement (TAVR). Methods: This study was retrospectively designed and includes 170 TAVR patients with a mean age of...
Gespeichert in:
| Veröffentlicht in: | Revista brasileira de cirurgia cardiovascular 2022 |
|---|---|
| Hauptverfasser: | , , , , , , , , |
| Format: | Artikel |
| Sprache: | por |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | |
| container_start_page | |
| container_title | Revista brasileira de cirurgia cardiovascular |
| container_volume | |
| creator | Katkat, Fahrettin Kalyoncuoglu, Muhsin Ozcan, Sevgi Tugrul, Sevil Abanus, Hanife Ince, Orhan Balli, Mehmet Sahin, Irfan Okuyan, Ertugrul |
| description | Abstract Objective: We aimed to investigate whether C-reactive protein to albumin ratio (CAR) predicts the early and late mortality in patients undergoing transcatheter aortic valve replacement (TAVR). Methods: This study was retrospectively designed and includes 170 TAVR patients with a mean age of 78.4±7.1 years. Patients were divided into 2 groups as those who died and those who survived, taking into account the follow-up period. Complete blood count, serum CRP and serum albumin were obtained on admission. The CAR value of all patients was calculated and the relationship of CAR with early (≤30 days) and late mortality (>30 days) was evaluated. Results: The median follow-up period was 19 [7-31] months (maximum 66 months). Early mortality was observed in 20 (11.8%) patients, whereas late mortality was observed in 39 (22.9%) patients, most of them male (61.1%, P=0.04). Non-survivors had greater CAR value, higher baseline serum CRP level and lower baseline albumin level than survivors (P |
| doi_str_mv | 10.21470/1678-9741-2020-0482 |
| format | Article |
| fullrecord | <record><control><sourceid>scielo</sourceid><recordid>TN_cdi_scielo_journals_S0102_76382022005002202</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><scielo_id>S0102_76382022005002202</scielo_id><sourcerecordid>S0102_76382022005002202</sourcerecordid><originalsourceid>FETCH-scielo_journals_S0102_763820220050022023</originalsourceid><addsrcrecordid>eNqVj01OwzAQhb0AifJzAxZzAZeJE5qwDAVEF0VVKGyjIZ0UF8dGtlspZ-GyGAmxZ_WeZuZ7eiPEZYZTlRUlXmWzspI3ZZFJhQolFpU6EpO_6Yk4DWGHqMq8won4msuGqYv6wLDyLrK2EB3U5m0_JNtQ1A4oQA1P7sAGFrY3NAwUnR_lLQXewJL8B3vonYcc5R2NsHQ-ktFxhBSxShFsY4AXu2G_ddpuYe3Jho7iO8dE1ulcd_BKJpVo-NNQx0NCzsVxTybwxa-eienD_Xr-KEOn2bh25_bepkX7jBmqtpzlVXpZIV7jj6j838A3nV1iOA</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype></control><display><type>article</type><title>C-Reactive Protein to Albumin Ratio as A Novel Inflammatory-Based Marker for 30-Day Mortality in Patients Undergoing Transcatheter Aortic Valve Replacement</title><source>DOAJ Directory of Open Access Journals</source><source>PubMed Central</source><source>PubMed Central Open Access</source><creator>Katkat, Fahrettin ; Kalyoncuoglu, Muhsin ; Ozcan, Sevgi ; Tugrul, Sevil ; Abanus, Hanife ; Ince, Orhan ; Balli, Mehmet ; Sahin, Irfan ; Okuyan, Ertugrul</creator><creatorcontrib>Katkat, Fahrettin ; Kalyoncuoglu, Muhsin ; Ozcan, Sevgi ; Tugrul, Sevil ; Abanus, Hanife ; Ince, Orhan ; Balli, Mehmet ; Sahin, Irfan ; Okuyan, Ertugrul</creatorcontrib><description>Abstract Objective: We aimed to investigate whether C-reactive protein to albumin ratio (CAR) predicts the early and late mortality in patients undergoing transcatheter aortic valve replacement (TAVR). Methods: This study was retrospectively designed and includes 170 TAVR patients with a mean age of 78.4±7.1 years. Patients were divided into 2 groups as those who died and those who survived, taking into account the follow-up period. Complete blood count, serum CRP and serum albumin were obtained on admission. The CAR value of all patients was calculated and the relationship of CAR with early (≤30 days) and late mortality (>30 days) was evaluated. Results: The median follow-up period was 19 [7-31] months (maximum 66 months). Early mortality was observed in 20 (11.8%) patients, whereas late mortality was observed in 39 (22.9%) patients, most of them male (61.1%, P=0.04). Non-survivors had greater CAR value, higher baseline serum CRP level and lower baseline albumin level than survivors (P<0.01, for all parameters). According to multivariate analysis models, CAR (HR: 1.020, P<0.01) and TVAR score (HR: 1.294, P<0.01) were found to be independent predictors of early mortality while CRP and albumin were not. The area under the curve (AUC) for CAR was 0.73 with a P <0.01. A CAR >15.6 predicted the early mortality with 80% sensitivity and 57% specificity. Conclusion: The novel inflammatory marker CAR can be used as a reliable marker in predicting 30-day mortality in patients undergoing TAVR.</description><identifier>ISSN: 1678-9741</identifier><identifier>DOI: 10.21470/1678-9741-2020-0482</identifier><language>por</language><publisher>Sociedade Brasileira de Cirurgia Cardiovascular</publisher><subject>CARDIAC & CARDIOVASCULAR SYSTEMS ; SURGERY</subject><ispartof>Revista brasileira de cirurgia cardiovascular, 2022</ispartof><rights>This work is licensed under a Creative Commons Attribution 4.0 International License.</rights><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>230,314,776,780,860,881,27901,27902</link.rule.ids></links><search><creatorcontrib>Katkat, Fahrettin</creatorcontrib><creatorcontrib>Kalyoncuoglu, Muhsin</creatorcontrib><creatorcontrib>Ozcan, Sevgi</creatorcontrib><creatorcontrib>Tugrul, Sevil</creatorcontrib><creatorcontrib>Abanus, Hanife</creatorcontrib><creatorcontrib>Ince, Orhan</creatorcontrib><creatorcontrib>Balli, Mehmet</creatorcontrib><creatorcontrib>Sahin, Irfan</creatorcontrib><creatorcontrib>Okuyan, Ertugrul</creatorcontrib><title>C-Reactive Protein to Albumin Ratio as A Novel Inflammatory-Based Marker for 30-Day Mortality in Patients Undergoing Transcatheter Aortic Valve Replacement</title><title>Revista brasileira de cirurgia cardiovascular</title><addtitle>Braz. J. Cardiovasc. Surg</addtitle><description>Abstract Objective: We aimed to investigate whether C-reactive protein to albumin ratio (CAR) predicts the early and late mortality in patients undergoing transcatheter aortic valve replacement (TAVR). Methods: This study was retrospectively designed and includes 170 TAVR patients with a mean age of 78.4±7.1 years. Patients were divided into 2 groups as those who died and those who survived, taking into account the follow-up period. Complete blood count, serum CRP and serum albumin were obtained on admission. The CAR value of all patients was calculated and the relationship of CAR with early (≤30 days) and late mortality (>30 days) was evaluated. Results: The median follow-up period was 19 [7-31] months (maximum 66 months). Early mortality was observed in 20 (11.8%) patients, whereas late mortality was observed in 39 (22.9%) patients, most of them male (61.1%, P=0.04). Non-survivors had greater CAR value, higher baseline serum CRP level and lower baseline albumin level than survivors (P<0.01, for all parameters). According to multivariate analysis models, CAR (HR: 1.020, P<0.01) and TVAR score (HR: 1.294, P<0.01) were found to be independent predictors of early mortality while CRP and albumin were not. The area under the curve (AUC) for CAR was 0.73 with a P <0.01. A CAR >15.6 predicted the early mortality with 80% sensitivity and 57% specificity. Conclusion: The novel inflammatory marker CAR can be used as a reliable marker in predicting 30-day mortality in patients undergoing TAVR.</description><subject>CARDIAC & CARDIOVASCULAR SYSTEMS</subject><subject>SURGERY</subject><issn>1678-9741</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><recordid>eNqVj01OwzAQhb0AifJzAxZzAZeJE5qwDAVEF0VVKGyjIZ0UF8dGtlspZ-GyGAmxZ_WeZuZ7eiPEZYZTlRUlXmWzspI3ZZFJhQolFpU6EpO_6Yk4DWGHqMq8won4msuGqYv6wLDyLrK2EB3U5m0_JNtQ1A4oQA1P7sAGFrY3NAwUnR_lLQXewJL8B3vonYcc5R2NsHQ-ktFxhBSxShFsY4AXu2G_ddpuYe3Jho7iO8dE1ulcd_BKJpVo-NNQx0NCzsVxTybwxa-eienD_Xr-KEOn2bh25_bepkX7jBmqtpzlVXpZIV7jj6j838A3nV1iOA</recordid><startdate>202201</startdate><enddate>202201</enddate><creator>Katkat, Fahrettin</creator><creator>Kalyoncuoglu, Muhsin</creator><creator>Ozcan, Sevgi</creator><creator>Tugrul, Sevil</creator><creator>Abanus, Hanife</creator><creator>Ince, Orhan</creator><creator>Balli, Mehmet</creator><creator>Sahin, Irfan</creator><creator>Okuyan, Ertugrul</creator><general>Sociedade Brasileira de Cirurgia Cardiovascular</general><scope>GPN</scope></search><sort><creationdate>202201</creationdate><title>C-Reactive Protein to Albumin Ratio as A Novel Inflammatory-Based Marker for 30-Day Mortality in Patients Undergoing Transcatheter Aortic Valve Replacement</title><author>Katkat, Fahrettin ; Kalyoncuoglu, Muhsin ; Ozcan, Sevgi ; Tugrul, Sevil ; Abanus, Hanife ; Ince, Orhan ; Balli, Mehmet ; Sahin, Irfan ; Okuyan, Ertugrul</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-scielo_journals_S0102_763820220050022023</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>por</language><creationdate>2022</creationdate><topic>CARDIAC & CARDIOVASCULAR SYSTEMS</topic><topic>SURGERY</topic><toplevel>online_resources</toplevel><creatorcontrib>Katkat, Fahrettin</creatorcontrib><creatorcontrib>Kalyoncuoglu, Muhsin</creatorcontrib><creatorcontrib>Ozcan, Sevgi</creatorcontrib><creatorcontrib>Tugrul, Sevil</creatorcontrib><creatorcontrib>Abanus, Hanife</creatorcontrib><creatorcontrib>Ince, Orhan</creatorcontrib><creatorcontrib>Balli, Mehmet</creatorcontrib><creatorcontrib>Sahin, Irfan</creatorcontrib><creatorcontrib>Okuyan, Ertugrul</creatorcontrib><collection>SciELO</collection><jtitle>Revista brasileira de cirurgia cardiovascular</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Katkat, Fahrettin</au><au>Kalyoncuoglu, Muhsin</au><au>Ozcan, Sevgi</au><au>Tugrul, Sevil</au><au>Abanus, Hanife</au><au>Ince, Orhan</au><au>Balli, Mehmet</au><au>Sahin, Irfan</au><au>Okuyan, Ertugrul</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>C-Reactive Protein to Albumin Ratio as A Novel Inflammatory-Based Marker for 30-Day Mortality in Patients Undergoing Transcatheter Aortic Valve Replacement</atitle><jtitle>Revista brasileira de cirurgia cardiovascular</jtitle><addtitle>Braz. J. Cardiovasc. Surg</addtitle><date>2022-01</date><risdate>2022</risdate><issn>1678-9741</issn><abstract>Abstract Objective: We aimed to investigate whether C-reactive protein to albumin ratio (CAR) predicts the early and late mortality in patients undergoing transcatheter aortic valve replacement (TAVR). Methods: This study was retrospectively designed and includes 170 TAVR patients with a mean age of 78.4±7.1 years. Patients were divided into 2 groups as those who died and those who survived, taking into account the follow-up period. Complete blood count, serum CRP and serum albumin were obtained on admission. The CAR value of all patients was calculated and the relationship of CAR with early (≤30 days) and late mortality (>30 days) was evaluated. Results: The median follow-up period was 19 [7-31] months (maximum 66 months). Early mortality was observed in 20 (11.8%) patients, whereas late mortality was observed in 39 (22.9%) patients, most of them male (61.1%, P=0.04). Non-survivors had greater CAR value, higher baseline serum CRP level and lower baseline albumin level than survivors (P<0.01, for all parameters). According to multivariate analysis models, CAR (HR: 1.020, P<0.01) and TVAR score (HR: 1.294, P<0.01) were found to be independent predictors of early mortality while CRP and albumin were not. The area under the curve (AUC) for CAR was 0.73 with a P <0.01. A CAR >15.6 predicted the early mortality with 80% sensitivity and 57% specificity. Conclusion: The novel inflammatory marker CAR can be used as a reliable marker in predicting 30-day mortality in patients undergoing TAVR.</abstract><pub>Sociedade Brasileira de Cirurgia Cardiovascular</pub><doi>10.21470/1678-9741-2020-0482</doi><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1678-9741 |
| ispartof | Revista brasileira de cirurgia cardiovascular, 2022 |
| issn | 1678-9741 |
| language | por |
| recordid | cdi_scielo_journals_S0102_76382022005002202 |
| source | DOAJ Directory of Open Access Journals; PubMed Central; PubMed Central Open Access |
| subjects | CARDIAC & CARDIOVASCULAR SYSTEMS SURGERY |
| title | C-Reactive Protein to Albumin Ratio as A Novel Inflammatory-Based Marker for 30-Day Mortality in Patients Undergoing Transcatheter Aortic Valve Replacement |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-03T00%3A11%3A53IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-scielo&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=C-Reactive%20Protein%20to%20Albumin%20Ratio%20as%20A%20Novel%20Inflammatory-Based%20Marker%20for%2030-Day%20Mortality%20in%20Patients%20Undergoing%20Transcatheter%20Aortic%20Valve%20Replacement&rft.jtitle=Revista%20brasileira%20de%20cirurgia%20cardiovascular&rft.au=Katkat,%20Fahrettin&rft.date=2022-01&rft.issn=1678-9741&rft_id=info:doi/10.21470/1678-9741-2020-0482&rft_dat=%3Cscielo%3ES0102_76382022005002202%3C/scielo%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rft_scielo_id=S0102_76382022005002202&rfr_iscdi=true |