Identification of a type I nitroreductase gene in non-virulent Trypanosoma rangeli

Trypanosomatid type I nitroreductases (NTRs), i.e., mitochondrial enzymes that metabolise nitroaromatic pro-drugs, are essential for parasite growth, infection, and survival. Here, a type I NTR of non-virulent protozoan Trypanosoma rangeli is described and compared to those of other trypanosomatids....

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Veröffentlicht in:	Memórias do Instituto Oswaldo Cruz 2017-07, Vol.112 (7), p.504-509
Hauptverfasser:	Montenegro, Marjorie, Cuervo, Claudia, Cardenas, Constanza, Duarte, Silvia, Díaz, Jenny R, Thomas, M Carmen, Lopez, Manuel C, Puerta, Concepcion J
Format:	Artikel
Sprache:	eng
Schlagworte:	Base Sequence DNA, Protozoan - genetics Genetic Variation - genetics Humans Nitroreductases - genetics PARASITOLOGY Sequence Analysis, DNA Short Communication TROPICAL MEDICINE Trypanosoma cruzi Trypanosoma rangeli Trypanosoma rangeli - enzymology Trypanosoma rangeli - genetics type I nitroreductase
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