Chagasic enteropathy

Involvement of the hollow organs of the digestive apparatus can occur in patients in the chronic phase of Chagas' disease. The basic mechanism is destruction of neurons of the enteric nervous system. Whereas megaesophagus and megacolon are the most notable and most extensively studied expressio...

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Veröffentlicht in:Revista da Sociedade Brasileira de Medicina Tropical 2004-05, Vol.37 (3), p.252-260
1. Verfasser: Meneghelli, Ulysses G
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description Involvement of the hollow organs of the digestive apparatus can occur in patients in the chronic phase of Chagas' disease. The basic mechanism is destruction of neurons of the enteric nervous system. Whereas megaesophagus and megacolon are the most notable and most extensively studied expressions of the digestive form of Chagas' disease, involvement of the small intestine (Chagasic enteropathy) is less frequent and less known than involvement of the two above mentioned entities. Chagasic enteropathy can be responsible for important clinical and laboratory manifestations resembling those of dyspeptic syndrome, intestinal pseudo-obstruction and bacterial overgrowth in the small intestine. Chagasic enteropathy also involves peculiar functional changes, especially those related to motor activity of the organ and to intestinal absorption of carbohydrates. In practice, the diagnosis is based on radiographic documentation of dilation of visceral segments. Treatment consists of clinical control of the above syndromes and, eventually, appropriate surgical operations.
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subjects Animals
Carbohydrates
Chagas Disease - diagnosis
Chagas Disease - physiopathology
Chagas Disease - therapy
Chronic Disease
Duodenal Diseases - diagnosis
Duodenal Diseases - physiopathology
Duodenal Diseases - therapy
Humans
Ileal Diseases - diagnosis
Ileal Diseases - physiopathology
Ileal Diseases - therapy
Intestinal Diseases, Parasitic - diagnosis
Intestinal Diseases, Parasitic - physiopathology
Intestinal Diseases, Parasitic - therapy
Jejunal Diseases - diagnosis
Jejunal Diseases - physiopathology
Jejunal Diseases - therapy
TROPICAL MEDICINE
Vector-borne diseases
title Chagasic enteropathy
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