Chagasic enteropathy
Involvement of the hollow organs of the digestive apparatus can occur in patients in the chronic phase of Chagas' disease. The basic mechanism is destruction of neurons of the enteric nervous system. Whereas megaesophagus and megacolon are the most notable and most extensively studied expressio...
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Veröffentlicht in: | Revista da Sociedade Brasileira de Medicina Tropical 2004-05, Vol.37 (3), p.252-260 |
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description | Involvement of the hollow organs of the digestive apparatus can occur in patients in the chronic phase of Chagas' disease. The basic mechanism is destruction of neurons of the enteric nervous system. Whereas megaesophagus and megacolon are the most notable and most extensively studied expressions of the digestive form of Chagas' disease, involvement of the small intestine (Chagasic enteropathy) is less frequent and less known than involvement of the two above mentioned entities. Chagasic enteropathy can be responsible for important clinical and laboratory manifestations resembling those of dyspeptic syndrome, intestinal pseudo-obstruction and bacterial overgrowth in the small intestine. Chagasic enteropathy also involves peculiar functional changes, especially those related to motor activity of the organ and to intestinal absorption of carbohydrates. In practice, the diagnosis is based on radiographic documentation of dilation of visceral segments. Treatment consists of clinical control of the above syndromes and, eventually, appropriate surgical operations. |
doi_str_mv | 10.1590/S0037-86822004000300012 |
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The basic mechanism is destruction of neurons of the enteric nervous system. Whereas megaesophagus and megacolon are the most notable and most extensively studied expressions of the digestive form of Chagas' disease, involvement of the small intestine (Chagasic enteropathy) is less frequent and less known than involvement of the two above mentioned entities. Chagasic enteropathy can be responsible for important clinical and laboratory manifestations resembling those of dyspeptic syndrome, intestinal pseudo-obstruction and bacterial overgrowth in the small intestine. Chagasic enteropathy also involves peculiar functional changes, especially those related to motor activity of the organ and to intestinal absorption of carbohydrates. In practice, the diagnosis is based on radiographic documentation of dilation of visceral segments. Treatment consists of clinical control of the above syndromes and, eventually, appropriate surgical operations.</description><identifier>ISSN: 0037-8682</identifier><identifier>ISSN: 1678-9849</identifier><identifier>EISSN: 0037-8682</identifier><identifier>EISSN: 1678-9849</identifier><identifier>DOI: 10.1590/S0037-86822004000300012</identifier><identifier>PMID: 15330067</identifier><language>eng</language><publisher>Brazil: Sociedade Brasileira de Medicina Tropical</publisher><subject>Animals ; Carbohydrates ; Chagas Disease - diagnosis ; Chagas Disease - physiopathology ; Chagas Disease - therapy ; Chronic Disease ; Duodenal Diseases - diagnosis ; Duodenal Diseases - physiopathology ; Duodenal Diseases - therapy ; Humans ; Ileal Diseases - diagnosis ; Ileal Diseases - physiopathology ; Ileal Diseases - therapy ; Intestinal Diseases, Parasitic - diagnosis ; Intestinal Diseases, Parasitic - physiopathology ; Intestinal Diseases, Parasitic - therapy ; Jejunal Diseases - diagnosis ; Jejunal Diseases - physiopathology ; Jejunal Diseases - therapy ; TROPICAL MEDICINE ; Vector-borne diseases</subject><ispartof>Revista da Sociedade Brasileira de Medicina Tropical, 2004-05, Vol.37 (3), p.252-260</ispartof><rights>Copyright Sociedade Brasileira de Medicina Tropical May/Jun 2004</rights><rights>This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3402-1a6c466b8043178cd0df145919f854bc6946a46371a70e2734cf95f14a28039e3</citedby><cites>FETCH-LOGICAL-c3402-1a6c466b8043178cd0df145919f854bc6946a46371a70e2734cf95f14a28039e3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>230,314,780,784,864,885,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/15330067$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Meneghelli, Ulysses G</creatorcontrib><title>Chagasic enteropathy</title><title>Revista da Sociedade Brasileira de Medicina Tropical</title><addtitle>Rev Soc Bras Med Trop</addtitle><description>Involvement of the hollow organs of the digestive apparatus can occur in patients in the chronic phase of Chagas' disease. The basic mechanism is destruction of neurons of the enteric nervous system. Whereas megaesophagus and megacolon are the most notable and most extensively studied expressions of the digestive form of Chagas' disease, involvement of the small intestine (Chagasic enteropathy) is less frequent and less known than involvement of the two above mentioned entities. Chagasic enteropathy can be responsible for important clinical and laboratory manifestations resembling those of dyspeptic syndrome, intestinal pseudo-obstruction and bacterial overgrowth in the small intestine. Chagasic enteropathy also involves peculiar functional changes, especially those related to motor activity of the organ and to intestinal absorption of carbohydrates. In practice, the diagnosis is based on radiographic documentation of dilation of visceral segments. Treatment consists of clinical control of the above syndromes and, eventually, appropriate surgical operations.</description><subject>Animals</subject><subject>Carbohydrates</subject><subject>Chagas Disease - diagnosis</subject><subject>Chagas Disease - physiopathology</subject><subject>Chagas Disease - therapy</subject><subject>Chronic Disease</subject><subject>Duodenal Diseases - diagnosis</subject><subject>Duodenal Diseases - physiopathology</subject><subject>Duodenal Diseases - therapy</subject><subject>Humans</subject><subject>Ileal Diseases - diagnosis</subject><subject>Ileal Diseases - physiopathology</subject><subject>Ileal Diseases - therapy</subject><subject>Intestinal Diseases, Parasitic - diagnosis</subject><subject>Intestinal Diseases, Parasitic - physiopathology</subject><subject>Intestinal Diseases, Parasitic - therapy</subject><subject>Jejunal Diseases - diagnosis</subject><subject>Jejunal Diseases - physiopathology</subject><subject>Jejunal Diseases - therapy</subject><subject>TROPICAL MEDICINE</subject><subject>Vector-borne diseases</subject><issn>0037-8682</issn><issn>1678-9849</issn><issn>0037-8682</issn><issn>1678-9849</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2004</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>8G5</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNp9kE1LAzEQhoMotlZvnlUQvG2dSbL5OMriFxQ8qOeQplm7ZdutSffQf290lyoKHkIS8jzvZIaQc4Qx5hqunwGYzJRQlAJwSLe0kO6R4e5h_8d5QI5iXABQyTQ9JAPMWRKEHJLTYm7fbKzchV9tfGjWdjPfHpOD0tbRn_T7iLze3b4UD9nk6f6xuJlkjnGgGVrhuBBTBZyhVG4GsxJ5rlGXKudTJzQXlgsm0UrwqTZ3pc4TYqkCpj0bkXGXG13l68YsmjasUkHz1Z75014SrjphHZr31seNWVbR-bq2K9-00QihMCkigZe_wF02cq5RMBQqUbKjXGhiDL4061AtbdgaBPM5538-ctbnt9Oln317_WDZBxi9cQY</recordid><startdate>200405</startdate><enddate>200405</enddate><creator>Meneghelli, Ulysses G</creator><general>Sociedade Brasileira de Medicina Tropical</general><general>Sociedade Brasileira de Medicina Tropical - 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diagnosis</topic><topic>Chagas Disease - physiopathology</topic><topic>Chagas Disease - therapy</topic><topic>Chronic Disease</topic><topic>Duodenal Diseases - diagnosis</topic><topic>Duodenal Diseases - physiopathology</topic><topic>Duodenal Diseases - therapy</topic><topic>Humans</topic><topic>Ileal Diseases - diagnosis</topic><topic>Ileal Diseases - physiopathology</topic><topic>Ileal Diseases - therapy</topic><topic>Intestinal Diseases, Parasitic - diagnosis</topic><topic>Intestinal Diseases, Parasitic - physiopathology</topic><topic>Intestinal Diseases, Parasitic - therapy</topic><topic>Jejunal Diseases - diagnosis</topic><topic>Jejunal Diseases - physiopathology</topic><topic>Jejunal Diseases - therapy</topic><topic>TROPICAL MEDICINE</topic><topic>Vector-borne diseases</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Meneghelli, Ulysses G</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Biotechnology Research Abstracts</collection><collection>Nursing & Allied Health Database</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Science Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>Technology Research Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Latin America & Iberia Database</collection><collection>ProQuest Central Korea</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>SciTech Premium Collection</collection><collection>Consumer Health Database (Alumni Edition)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Consumer Health Database</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Research Library</collection><collection>Science Database</collection><collection>Research Library (Corporate)</collection><collection>Nursing & Allied Health Premium</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - 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The basic mechanism is destruction of neurons of the enteric nervous system. Whereas megaesophagus and megacolon are the most notable and most extensively studied expressions of the digestive form of Chagas' disease, involvement of the small intestine (Chagasic enteropathy) is less frequent and less known than involvement of the two above mentioned entities. Chagasic enteropathy can be responsible for important clinical and laboratory manifestations resembling those of dyspeptic syndrome, intestinal pseudo-obstruction and bacterial overgrowth in the small intestine. Chagasic enteropathy also involves peculiar functional changes, especially those related to motor activity of the organ and to intestinal absorption of carbohydrates. In practice, the diagnosis is based on radiographic documentation of dilation of visceral segments. Treatment consists of clinical control of the above syndromes and, eventually, appropriate surgical operations.</abstract><cop>Brazil</cop><pub>Sociedade Brasileira de Medicina Tropical</pub><pmid>15330067</pmid><doi>10.1590/S0037-86822004000300012</doi><tpages>9</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Animals Carbohydrates Chagas Disease - diagnosis Chagas Disease - physiopathology Chagas Disease - therapy Chronic Disease Duodenal Diseases - diagnosis Duodenal Diseases - physiopathology Duodenal Diseases - therapy Humans Ileal Diseases - diagnosis Ileal Diseases - physiopathology Ileal Diseases - therapy Intestinal Diseases, Parasitic - diagnosis Intestinal Diseases, Parasitic - physiopathology Intestinal Diseases, Parasitic - therapy Jejunal Diseases - diagnosis Jejunal Diseases - physiopathology Jejunal Diseases - therapy TROPICAL MEDICINE Vector-borne diseases |
title | Chagasic enteropathy |
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