Subcutaneoous phaeohyphomycosis by Exophiala jeanselmei in a cardiac transplant recipient
We report a case of phaeohyphomycosis caused by Exophiala jeanselmei in a cardiac transplant recipient maintained on immunosuppressive therapy with mycophenolate mofetil tacrolimus and prednisone. The lesion began after trauma on the right leg that evolved to multiple lesions with nodules and ulcers...
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| Veröffentlicht in: | Revista do Instituto de Medicina Tropical de São Paulo 2005-02, Vol.47 (1), p.55-57 |
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| container_title | Revista do Instituto de Medicina Tropical de São Paulo |
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| creator | Silva, Maria do Rosário R Fernandes, Orionalda de F L Costa, Carolina R Chaul, Aiçar Morgado, Luciano F Fleury-Júnior, Luis Fernando Costa, Maurício B |
| description | We report a case of phaeohyphomycosis caused by Exophiala jeanselmei in a cardiac transplant recipient maintained on immunosuppressive therapy with mycophenolate mofetil tacrolimus and prednisone. The lesion began after trauma on the right leg that evolved to multiple lesions with nodules and ulcers. Diagnosis was performed by histological examination and culture of pus from skin lesions. Treatment consisted of itraconazole (200 mg/day) for three months with no improvement and subsequently with amphotericin B (0.5 mg/Kg per day to a total of 3.8 g intravenously). After four months of treatment, the lesions showed marked improvement with reduction in the swelling and healing of sinuses and residual scarring. |
| doi_str_mv | 10.1590/S0036-46652005000100009 |
| format | Article |
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After four months of treatment, the lesions showed marked improvement with reduction in the swelling and healing of sinuses and residual scarring.</description><subject>Amphotericin B - therapeutic use</subject><subject>Antifungal Agents - therapeutic use</subject><subject>Dermatomycoses - drug therapy</subject><subject>Dermatomycoses - microbiology</subject><subject>Dermatomycoses - pathology</subject><subject>Exophiala</subject><subject>Heart Transplantation</subject><subject>Humans</subject><subject>Immunocompromised Host</subject><subject>Immunosuppressive Agents - therapeutic use</subject><subject>Itraconazole - therapeutic use</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Subcutaneous Tissue - microbiology</subject><subject>TROPICAL MEDICINE</subject><issn>0036-4665</issn><issn>1678-9946</issn><issn>0036-4665</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2005</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9UU1PwzAMjRCIweAvQE7cOpI2H8sRTeNDmsRhcOBUJamrZWqbkrQS_fd0bAIkJA6WLfs9P-sZoWtKZpQrcrsmJBMJE4KnhHBCCB2DqCN09j04_lVP0HmM2x2CKHGKJpTLVDHJz9Dbuje273QD3vcRtxsNfjO0G18P1kcXsRnw8sO3G6crjbegmwhVDQ67BmtsdSictrgLY7-tdNPhANa1DpruAp2UuopwechT9Hq_fFk8Jqvnh6fF3SqxKWMqoWy8srQiNbbIQBswnBphGLeCkoJJBqVIUyLmwsgyzeayUHJOIVOlZmNBsima7fdG66Dy-db3oRkF8y-P8j8ejYSbPaEN_r2H2OW1ixaqamdCH3MhGVcZ5SNQ7oE2-BgDlHkbXK3DkFOS797wj8TVQaI3NRQ_vIPv2Scwu4D3</recordid><startdate>20050201</startdate><enddate>20050201</enddate><creator>Silva, Maria do Rosário R</creator><creator>Fernandes, Orionalda de F L</creator><creator>Costa, Carolina R</creator><creator>Chaul, Aiçar</creator><creator>Morgado, Luciano F</creator><creator>Fleury-Júnior, Luis Fernando</creator><creator>Costa, Maurício B</creator><general>Instituto de Medicina Tropical</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>GPN</scope></search><sort><creationdate>20050201</creationdate><title>Subcutaneoous phaeohyphomycosis by Exophiala jeanselmei in a cardiac transplant recipient</title><author>Silva, Maria do Rosário R ; 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| source | MEDLINE; DOAJ Directory of Open Access Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals |
| subjects | Amphotericin B - therapeutic use Antifungal Agents - therapeutic use Dermatomycoses - drug therapy Dermatomycoses - microbiology Dermatomycoses - pathology Exophiala Heart Transplantation Humans Immunocompromised Host Immunosuppressive Agents - therapeutic use Itraconazole - therapeutic use Male Middle Aged Subcutaneous Tissue - microbiology TROPICAL MEDICINE |
| title | Subcutaneoous phaeohyphomycosis by Exophiala jeanselmei in a cardiac transplant recipient |
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