Modification in body weight associated with antiepileptic drugs
Antiepileptic drugs (AED) may cause body weight changes. To evaluate the dietary habits and body weight associated with AED in epileptic patients. Sixty-six patients were subjected to two interviews, and had their weight and body mass index calculated and compared at both times, interval between six...
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| Veröffentlicht in: | Arquivos de neuro-psiquiatria 2010-04, Vol.68 (2), p.277-281 |
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| creator | Gaspari, Camilla N De Guerreiro, Carlos A M |
| description | Antiepileptic drugs (AED) may cause body weight changes.
To evaluate the dietary habits and body weight associated with AED in epileptic patients.
Sixty-six patients were subjected to two interviews, and had their weight and body mass index calculated and compared at both times, interval between six to eight months.
It was observed that 59.1% showed weight gain. The patients who had no weight gain had a greater proportion of individuals who engaged in some form of physical activity. However, of the 45 patients who maintained their initial dietary and medication pattern, 75.6% recorded a weight gain. Weight gain was seen in 66.7% of patients on carbamazepine (n=18), 60% on valproate (n=5), 50% on carbamazepine+clobazam treatment (n=14), and 58.3% of patients on other(s) polytherapy (n=12).
The patient should be alerted to possible weight gain, and should be advised about dieting and participating in regular physical activity. |
| doi_str_mv | 10.1590/S0004-282X2010000200024 |
| format | Article |
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To evaluate the dietary habits and body weight associated with AED in epileptic patients.
Sixty-six patients were subjected to two interviews, and had their weight and body mass index calculated and compared at both times, interval between six to eight months.
It was observed that 59.1% showed weight gain. The patients who had no weight gain had a greater proportion of individuals who engaged in some form of physical activity. However, of the 45 patients who maintained their initial dietary and medication pattern, 75.6% recorded a weight gain. Weight gain was seen in 66.7% of patients on carbamazepine (n=18), 60% on valproate (n=5), 50% on carbamazepine+clobazam treatment (n=14), and 58.3% of patients on other(s) polytherapy (n=12).
The patient should be alerted to possible weight gain, and should be advised about dieting and participating in regular physical activity.</description><identifier>ISSN: 0004-282X</identifier><identifier>ISSN: 1678-4227</identifier><identifier>EISSN: 1678-4227</identifier><identifier>EISSN: 0004-282X</identifier><identifier>DOI: 10.1590/S0004-282X2010000200024</identifier><identifier>PMID: 20464300</identifier><language>eng</language><publisher>Brazil: Academia Brasileira de Neurologia - ABNEURO</publisher><subject>Adult ; Anticonvulsants - adverse effects ; Anticonvulsants - therapeutic use ; Body Mass Index ; Carbamazepine - adverse effects ; Carbamazepine - therapeutic use ; Epilepsy - drug therapy ; Female ; Humans ; Male ; NEUROSCIENCES ; PSYCHIATRY ; Valproic Acid - adverse effects ; Valproic Acid - therapeutic use ; Weight Gain - drug effects</subject><ispartof>Arquivos de neuro-psiquiatria, 2010-04, Vol.68 (2), p.277-281</ispartof><rights>This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c362t-db704aa18ba69350315c1883789c698ebb3acd239c15745ec4f3e5e8edaf1a3f3</citedby><cites>FETCH-LOGICAL-c362t-db704aa18ba69350315c1883789c698ebb3acd239c15745ec4f3e5e8edaf1a3f3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>230,314,780,784,864,885,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/20464300$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Gaspari, Camilla N De</creatorcontrib><creatorcontrib>Guerreiro, Carlos A M</creatorcontrib><title>Modification in body weight associated with antiepileptic drugs</title><title>Arquivos de neuro-psiquiatria</title><addtitle>Arq Neuropsiquiatr</addtitle><description>Antiepileptic drugs (AED) may cause body weight changes.
To evaluate the dietary habits and body weight associated with AED in epileptic patients.
Sixty-six patients were subjected to two interviews, and had their weight and body mass index calculated and compared at both times, interval between six to eight months.
It was observed that 59.1% showed weight gain. The patients who had no weight gain had a greater proportion of individuals who engaged in some form of physical activity. However, of the 45 patients who maintained their initial dietary and medication pattern, 75.6% recorded a weight gain. Weight gain was seen in 66.7% of patients on carbamazepine (n=18), 60% on valproate (n=5), 50% on carbamazepine+clobazam treatment (n=14), and 58.3% of patients on other(s) polytherapy (n=12).
The patient should be alerted to possible weight gain, and should be advised about dieting and participating in regular physical activity.</description><subject>Adult</subject><subject>Anticonvulsants - adverse effects</subject><subject>Anticonvulsants - therapeutic use</subject><subject>Body Mass Index</subject><subject>Carbamazepine - adverse effects</subject><subject>Carbamazepine - therapeutic use</subject><subject>Epilepsy - drug therapy</subject><subject>Female</subject><subject>Humans</subject><subject>Male</subject><subject>NEUROSCIENCES</subject><subject>PSYCHIATRY</subject><subject>Valproic Acid - adverse effects</subject><subject>Valproic Acid - therapeutic use</subject><subject>Weight Gain - drug effects</subject><issn>0004-282X</issn><issn>1678-4227</issn><issn>1678-4227</issn><issn>0004-282X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2010</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkctOwzAQRS0EoqXwC5AdqxQ_Y2eFUMVLKmIBSOwsx5m0rtK4xI6q_j0pLWyQYDGaWZw7M7oXoQuCx0Tk-OoFY8xTqug7xaSfMd0WP0BDkkmVckrlIRr-QAN0EsJiS-S5PEYDinnGGcZDdP3kS1c5a6LzTeKapPDlJlmDm81jYkLw1pkIZbJ2cZ6YJjpYuRpW0dmkbLtZOEVHlakDnO37CL3d3b5OHtLp8_3j5GaaWpbRmJaFxNwYogqT5UxgRoQlSjGpcpvlCoqCGVtSllsiJBdgecVAgILSVMSwio3QeLc3WAe11wvftU1_UH85oX850Qsud4JV6z86CFEvXbBQ16YB3wUtBReMZgz_TzImiFRC9qTckbb1IbRQ6VXrlqbdaIL1Npc_vjnf3-iKJZQ_uu8g2CfyjoWg</recordid><startdate>201004</startdate><enddate>201004</enddate><creator>Gaspari, Camilla N De</creator><creator>Guerreiro, Carlos A M</creator><general>Academia Brasileira de Neurologia - ABNEURO</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>7TK</scope><scope>GPN</scope></search><sort><creationdate>201004</creationdate><title>Modification in body weight associated with antiepileptic drugs</title><author>Gaspari, Camilla N De ; Guerreiro, Carlos A M</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c362t-db704aa18ba69350315c1883789c698ebb3acd239c15745ec4f3e5e8edaf1a3f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2010</creationdate><topic>Adult</topic><topic>Anticonvulsants - adverse effects</topic><topic>Anticonvulsants - therapeutic use</topic><topic>Body Mass Index</topic><topic>Carbamazepine - adverse effects</topic><topic>Carbamazepine - therapeutic use</topic><topic>Epilepsy - drug therapy</topic><topic>Female</topic><topic>Humans</topic><topic>Male</topic><topic>NEUROSCIENCES</topic><topic>PSYCHIATRY</topic><topic>Valproic Acid - adverse effects</topic><topic>Valproic Acid - therapeutic use</topic><topic>Weight Gain - drug effects</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Gaspari, Camilla N De</creatorcontrib><creatorcontrib>Guerreiro, Carlos A M</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>Neurosciences Abstracts</collection><collection>SciELO</collection><jtitle>Arquivos de neuro-psiquiatria</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Gaspari, Camilla N De</au><au>Guerreiro, Carlos A M</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Modification in body weight associated with antiepileptic drugs</atitle><jtitle>Arquivos de neuro-psiquiatria</jtitle><addtitle>Arq Neuropsiquiatr</addtitle><date>2010-04</date><risdate>2010</risdate><volume>68</volume><issue>2</issue><spage>277</spage><epage>281</epage><pages>277-281</pages><issn>0004-282X</issn><issn>1678-4227</issn><eissn>1678-4227</eissn><eissn>0004-282X</eissn><abstract>Antiepileptic drugs (AED) may cause body weight changes.
To evaluate the dietary habits and body weight associated with AED in epileptic patients.
Sixty-six patients were subjected to two interviews, and had their weight and body mass index calculated and compared at both times, interval between six to eight months.
It was observed that 59.1% showed weight gain. The patients who had no weight gain had a greater proportion of individuals who engaged in some form of physical activity. However, of the 45 patients who maintained their initial dietary and medication pattern, 75.6% recorded a weight gain. Weight gain was seen in 66.7% of patients on carbamazepine (n=18), 60% on valproate (n=5), 50% on carbamazepine+clobazam treatment (n=14), and 58.3% of patients on other(s) polytherapy (n=12).
The patient should be alerted to possible weight gain, and should be advised about dieting and participating in regular physical activity.</abstract><cop>Brazil</cop><pub>Academia Brasileira de Neurologia - ABNEURO</pub><pmid>20464300</pmid><doi>10.1590/S0004-282X2010000200024</doi><tpages>5</tpages><oa>free_for_read</oa></addata></record> |
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| identifier | ISSN: 0004-282X |
| ispartof | Arquivos de neuro-psiquiatria, 2010-04, Vol.68 (2), p.277-281 |
| issn | 0004-282X 1678-4227 1678-4227 0004-282X |
| language | eng |
| recordid | cdi_scielo_journals_S0004_282X2010000200024 |
| source | MEDLINE; DOAJ Directory of Open Access Journals; EZB-FREE-00999 freely available EZB journals |
| subjects | Adult Anticonvulsants - adverse effects Anticonvulsants - therapeutic use Body Mass Index Carbamazepine - adverse effects Carbamazepine - therapeutic use Epilepsy - drug therapy Female Humans Male NEUROSCIENCES PSYCHIATRY Valproic Acid - adverse effects Valproic Acid - therapeutic use Weight Gain - drug effects |
| title | Modification in body weight associated with antiepileptic drugs |
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