Evaluation of unilateral corneal collagen cross-linking on fellow untreated eyes of patients with keratoconus
This study aimed to examine the effects of unilateral corneal collagen cross-linking treatment on visual acuity and the topographic findings of the fellow untreated eye of patients who had bilateral progressive keratoconus. Patients with progressive keratoconus who underwent cross-linking treatment...
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Veröffentlicht in: | Arquivos brasileiros de oftalmologia 2024-01, Vol.87 (3) |
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creator | Akçay, Emine Delioğlu, Ezgi Naz Ensari Kars, Meltem Ece Demir, Pervin Çağıl, Nurullah |
description | This study aimed to examine the effects of unilateral corneal collagen cross-linking treatment on visual acuity and the topographic findings of the fellow untreated eye of patients who had bilateral progressive keratoconus.
Patients with progressive keratoconus who underwent cross-linking treatment were screened retrospectively. A total of 188 untreated eyes of 188 patients whose eyes were treated unilaterally with either standard or accelerated cross-linking and refused cross-linking procedure for the fellow eye were included. Visual acuity and topographic findings of the fellow untreated eyes were obtained preoperatively and postoperatively at the 1st, 3rd, 6th, 12th, 24th, 30th, and 36th months.
The change over time of variables examined was similar in the untreated eyes of patients who received standard and accelerated cross-linking methods (p>0.05). At the 12th month, 136 (95.8%) untreated eyes were stable according to progression criteria. Only 4 (8%) eyes were progressive at the 24th month. No progression was observed in any of the 16 patients with a 36-month follow up.
The results showed that the fellow untreated eyes of patients with bilateral progressive keratoconus did not have significant progression rates after unilateral cross-linking treatment. |
doi_str_mv | 10.5935/0004-2749.2022-0004 |
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Patients with progressive keratoconus who underwent cross-linking treatment were screened retrospectively. A total of 188 untreated eyes of 188 patients whose eyes were treated unilaterally with either standard or accelerated cross-linking and refused cross-linking procedure for the fellow eye were included. Visual acuity and topographic findings of the fellow untreated eyes were obtained preoperatively and postoperatively at the 1st, 3rd, 6th, 12th, 24th, 30th, and 36th months.
The change over time of variables examined was similar in the untreated eyes of patients who received standard and accelerated cross-linking methods (p>0.05). At the 12th month, 136 (95.8%) untreated eyes were stable according to progression criteria. Only 4 (8%) eyes were progressive at the 24th month. No progression was observed in any of the 16 patients with a 36-month follow up.
The results showed that the fellow untreated eyes of patients with bilateral progressive keratoconus did not have significant progression rates after unilateral cross-linking treatment.</description><identifier>ISSN: 0004-2749</identifier><identifier>ISSN: 1678-2925</identifier><identifier>EISSN: 1678-2925</identifier><identifier>DOI: 10.5935/0004-2749.2022-0004</identifier><identifier>PMID: 36350908</identifier><language>eng</language><publisher>Brazil: Conselho Brasileiro de Oftalmologia</publisher><subject>OPHTHALMOLOGY ; Original</subject><ispartof>Arquivos brasileiros de oftalmologia, 2024-01, Vol.87 (3)</ispartof><rights>This work is licensed under a Creative Commons Attribution 4.0 International License.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><orcidid>0000-0002-2056-8141</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>230,314,780,784,885,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/36350908$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Akçay, Emine</creatorcontrib><creatorcontrib>Delioğlu, Ezgi Naz Ensari</creatorcontrib><creatorcontrib>Kars, Meltem Ece</creatorcontrib><creatorcontrib>Demir, Pervin</creatorcontrib><creatorcontrib>Çağıl, Nurullah</creatorcontrib><title>Evaluation of unilateral corneal collagen cross-linking on fellow untreated eyes of patients with keratoconus</title><title>Arquivos brasileiros de oftalmologia</title><addtitle>Arq Bras Oftalmol</addtitle><description>This study aimed to examine the effects of unilateral corneal collagen cross-linking treatment on visual acuity and the topographic findings of the fellow untreated eye of patients who had bilateral progressive keratoconus.
Patients with progressive keratoconus who underwent cross-linking treatment were screened retrospectively. A total of 188 untreated eyes of 188 patients whose eyes were treated unilaterally with either standard or accelerated cross-linking and refused cross-linking procedure for the fellow eye were included. Visual acuity and topographic findings of the fellow untreated eyes were obtained preoperatively and postoperatively at the 1st, 3rd, 6th, 12th, 24th, 30th, and 36th months.
The change over time of variables examined was similar in the untreated eyes of patients who received standard and accelerated cross-linking methods (p>0.05). At the 12th month, 136 (95.8%) untreated eyes were stable according to progression criteria. Only 4 (8%) eyes were progressive at the 24th month. No progression was observed in any of the 16 patients with a 36-month follow up.
The results showed that the fellow untreated eyes of patients with bilateral progressive keratoconus did not have significant progression rates after unilateral cross-linking treatment.</description><subject>OPHTHALMOLOGY</subject><subject>Original</subject><issn>0004-2749</issn><issn>1678-2925</issn><issn>1678-2925</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><recordid>eNpVUU1P3DAQtSqqstD-AqQqRy7Zju04iU8IIQpISD20PVuOd7wYvPbWTkD8-zq7sGpPo5Hfl98QckZhKSQX3wCgqVnXyCUDxup5_UAWtO36mkkmjsjigDgmJzk_ArBGSvGJHPOWC5DQL8jm-ln7SY8uhiraagrO6xGT9pWJKeBueq_XGCqTYs61d-HJhXVV8Ba9jy-FMyYspFWFr5hnlW3RwzDm6sWND9VTkRujiWHKn8lHq33GL2_zlPz-fv3r6ra-_3Fzd3V5XxsuxVgj2p5C01AtJDSitb01nKLR1lLe0aGXQ78ayg-MbfVqYIxJwbHTtAVBdTvwU7Lc62bj0Ef1GKcUiqH6OVei5krmzgAEUMpAFsLFnrCdhg2uTElfOlDb5DY6vaqonfr_JbgHtY7PitKWdSBpUTh_U0jxz4R5VBuXTWlIB4xTLp68aSnnVBQo30N3jSa0Bx8Kaj6tOqRUc8zdWlhf_4144Lzfkv8FaJafiw</recordid><startdate>20240101</startdate><enddate>20240101</enddate><creator>Akçay, Emine</creator><creator>Delioğlu, Ezgi Naz Ensari</creator><creator>Kars, Meltem Ece</creator><creator>Demir, Pervin</creator><creator>Çağıl, Nurullah</creator><general>Conselho Brasileiro de Oftalmologia</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope><scope>GPN</scope><orcidid>https://orcid.org/0000-0002-2056-8141</orcidid></search><sort><creationdate>20240101</creationdate><title>Evaluation of unilateral corneal collagen cross-linking on fellow untreated eyes of patients with keratoconus</title><author>Akçay, Emine ; Delioğlu, Ezgi Naz Ensari ; Kars, Meltem Ece ; Demir, Pervin ; Çağıl, Nurullah</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c395t-eef810441a590456f8fc31ecaff1371b89b8db509cf6adb222953e7a16051a6b3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2024</creationdate><topic>OPHTHALMOLOGY</topic><topic>Original</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Akçay, Emine</creatorcontrib><creatorcontrib>Delioğlu, Ezgi Naz Ensari</creatorcontrib><creatorcontrib>Kars, Meltem Ece</creatorcontrib><creatorcontrib>Demir, Pervin</creatorcontrib><creatorcontrib>Çağıl, Nurullah</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><collection>SciELO</collection><jtitle>Arquivos brasileiros de oftalmologia</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Akçay, Emine</au><au>Delioğlu, Ezgi Naz Ensari</au><au>Kars, Meltem Ece</au><au>Demir, Pervin</au><au>Çağıl, Nurullah</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Evaluation of unilateral corneal collagen cross-linking on fellow untreated eyes of patients with keratoconus</atitle><jtitle>Arquivos brasileiros de oftalmologia</jtitle><addtitle>Arq Bras Oftalmol</addtitle><date>2024-01-01</date><risdate>2024</risdate><volume>87</volume><issue>3</issue><issn>0004-2749</issn><issn>1678-2925</issn><eissn>1678-2925</eissn><abstract>This study aimed to examine the effects of unilateral corneal collagen cross-linking treatment on visual acuity and the topographic findings of the fellow untreated eye of patients who had bilateral progressive keratoconus.
Patients with progressive keratoconus who underwent cross-linking treatment were screened retrospectively. A total of 188 untreated eyes of 188 patients whose eyes were treated unilaterally with either standard or accelerated cross-linking and refused cross-linking procedure for the fellow eye were included. Visual acuity and topographic findings of the fellow untreated eyes were obtained preoperatively and postoperatively at the 1st, 3rd, 6th, 12th, 24th, 30th, and 36th months.
The change over time of variables examined was similar in the untreated eyes of patients who received standard and accelerated cross-linking methods (p>0.05). At the 12th month, 136 (95.8%) untreated eyes were stable according to progression criteria. Only 4 (8%) eyes were progressive at the 24th month. No progression was observed in any of the 16 patients with a 36-month follow up.
The results showed that the fellow untreated eyes of patients with bilateral progressive keratoconus did not have significant progression rates after unilateral cross-linking treatment.</abstract><cop>Brazil</cop><pub>Conselho Brasileiro de Oftalmologia</pub><pmid>36350908</pmid><doi>10.5935/0004-2749.2022-0004</doi><orcidid>https://orcid.org/0000-0002-2056-8141</orcidid><oa>free_for_read</oa></addata></record> |
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title | Evaluation of unilateral corneal collagen cross-linking on fellow untreated eyes of patients with keratoconus |
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