Simultaneous evaluation of in vivo glucocorticoid sensitivity and expression of glucocorticoid receptor alpha-isoform in rheumatoid arthritis patients

To analyze glucocorticoid (GC) sensitivity using intravenous very low dose dexamethasone suppression test (IV-VLD-DST) in patients with rheumatoid arthritis (RA) and its correlation with glucocorticoid receptor alpha-isoform (GRalpha) gene expression. We evaluated 20 healthy controls and 32 RA patie...

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Veröffentlicht in:	Arquivos brasileiros de endocrinologia e metabologia 2009-02, Vol.53 (1), p.24-30
Hauptverfasser:	Cobra, Jayme F, Melo, Murilo R, Faria, Claudia D C, Longui, Carlos Alberto, Monte, Osmar
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Analysis of Variance Arthritis, Rheumatoid - drug therapy Arthritis, Rheumatoid - genetics Case-Control Studies Dexamethasone - pharmacology Drug Resistance - physiology ENDOCRINOLOGY & METABOLISM Female Glucocorticoids - pharmacology Humans Hydrocortisone - blood Male Receptors, Glucocorticoid - drug effects Receptors, Glucocorticoid - genetics
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