The Half-Life of Endogenous Immunoreactive ACTH in Rat Plasma 1

Summary A radioimmunoassay for ACTH in the rat, which has previously been shown to provide close agreement with bioassay, was used to determine the disappearance rate of ACTH from the plasma of male rats following hypophysectomy under ether anesthesia. The calculated half-life of the immunoreactive...

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Veröffentlicht in:Proceedings of the Society for Experimental Biology and Medicine 1972-03, Vol.139 (3), p.972-974
Hauptverfasser: Cook, D. M., Greer, M. A., Kendall, J. W.
Format: Artikel
Sprache:eng
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Zusammenfassung:Summary A radioimmunoassay for ACTH in the rat, which has previously been shown to provide close agreement with bioassay, was used to determine the disappearance rate of ACTH from the plasma of male rats following hypophysectomy under ether anesthesia. The calculated half-life of the immunoreactive ACTH was 5 min.
ISSN:0037-9727
1535-3699
DOI:10.3181/00379727-139-36278