Acute Effect of Metal Ions on Uptake of Alpha-Aminoisobutyric Acid (AIB) by Rat Parathyroids in vivo.

Acute Effect of Metal Ions on Uptake of Alpha-Aminoisobutyric Acid (AIB) by Rat Parathyroids in vivo.

Summary Acute increases in serum calcium concentration produced by administration of calcium salts, parathyroid extract or high dosages of dihydrotachysterol generally resulted in a decrease in the uptake of AIB by the rat parathyroids in vivo. Acute decreases in serum calcium concentration produced...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Experimental biology and medicine (Maywood, N.J.) N.J.), 1966-05, Vol.122 (1), p.285-290
Hauptverfasser: Au, William Y. W., Engerman, Judith R., Risz, Lawrence G.
Format: Artikel
Sprache:eng
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 290
container_issue 1
container_start_page 285
container_title Experimental biology and medicine (Maywood, N.J.)
container_volume 122
creator Au, William Y. W.
Engerman, Judith R.
Risz, Lawrence G.
description Summary Acute increases in serum calcium concentration produced by administration of calcium salts, parathyroid extract or high dosages of dihydrotachysterol generally resulted in a decrease in the uptake of AIB by the rat parathyroids in vivo. Acute decreases in serum calcium concentration produced by administration of sodium oxalate, sodium phosphate, or thyrocalcitonin resulted in increases in the uptake of AIB by the parathyroids. Large increases in serum magnesium or strontium concentration also suppressed parathyroid AIB uptake. Administration of EDTA to decrease serum calcium concentration resulted in variable effect on parathyroid AIB uptake. This study provides further direct evidence for a negative feedback control of parathyroid function by serum calcium concentration.
doi_str_mv 10.3181/00379727-122-31114
format Article
fullrecord <record><control><sourceid>sage_cross</sourceid><recordid>TN_cdi_sage_journals_10_3181_00379727_122_31114</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sage_id>10.3181_00379727-122-31114</sage_id><sourcerecordid>10.3181_00379727-122-31114</sourcerecordid><originalsourceid>FETCH-LOGICAL-c285t-4708f7778797d71fa119f5923838716b39ff159244571e23189dc477bf4277993</originalsourceid><addsrcrecordid>eNp9kMFOwzAQRC0EEqXwA5x8hIPbrJ1042OoClQqAiF6jpzUpi5tXNlupfw9CYUrp9WsZlY7j5BbSEYCchgniUCJHBlwzgQApGdkAJnImJhIeU4GvYH1jktyFcImSSBDPhkQXdSHqOnMGF1H6gx90VFt6dw1gbqGLvdRfel-X2z3a8WKnW2cDa46xNbbmha1XdG7Yv5wT6uWvqtI35RXcd16Z1eB2oYe7dGNrsmFUdugb37nkCwfZx_TZ7Z4fZpPiwWreZ5FlmKSG0TMuy4rBKMApMkkF7nIESaVkMZAp9M0Q9C8ay5XdYpYmZQjSimGhJ_u1t6F4LUp997ulG9LSMoeVPkHquxAlT-gutD4FArqU5cbd_BN9-N_iW-NF2YG</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype></control><display><type>article</type><title>Acute Effect of Metal Ions on Uptake of Alpha-Aminoisobutyric Acid (AIB) by Rat Parathyroids in vivo.</title><source>Alma/SFX Local Collection</source><creator>Au, William Y. W. ; Engerman, Judith R. ; Risz, Lawrence G.</creator><creatorcontrib>Au, William Y. W. ; Engerman, Judith R. ; Risz, Lawrence G.</creatorcontrib><description>Summary Acute increases in serum calcium concentration produced by administration of calcium salts, parathyroid extract or high dosages of dihydrotachysterol generally resulted in a decrease in the uptake of AIB by the rat parathyroids in vivo. Acute decreases in serum calcium concentration produced by administration of sodium oxalate, sodium phosphate, or thyrocalcitonin resulted in increases in the uptake of AIB by the parathyroids. Large increases in serum magnesium or strontium concentration also suppressed parathyroid AIB uptake. Administration of EDTA to decrease serum calcium concentration resulted in variable effect on parathyroid AIB uptake. This study provides further direct evidence for a negative feedback control of parathyroid function by serum calcium concentration.</description><identifier>ISSN: 0037-9727</identifier><identifier>ISSN: 1535-3702</identifier><identifier>EISSN: 1535-3699</identifier><identifier>DOI: 10.3181/00379727-122-31114</identifier><language>eng</language><publisher>London, England: SAGE Publications</publisher><ispartof>Experimental biology and medicine (Maywood, N.J.), 1966-05, Vol.122 (1), p.285-290</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c285t-4708f7778797d71fa119f5923838716b39ff159244571e23189dc477bf4277993</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids></links><search><creatorcontrib>Au, William Y. W.</creatorcontrib><creatorcontrib>Engerman, Judith R.</creatorcontrib><creatorcontrib>Risz, Lawrence G.</creatorcontrib><title>Acute Effect of Metal Ions on Uptake of Alpha-Aminoisobutyric Acid (AIB) by Rat Parathyroids in vivo.</title><title>Experimental biology and medicine (Maywood, N.J.)</title><description>Summary Acute increases in serum calcium concentration produced by administration of calcium salts, parathyroid extract or high dosages of dihydrotachysterol generally resulted in a decrease in the uptake of AIB by the rat parathyroids in vivo. Acute decreases in serum calcium concentration produced by administration of sodium oxalate, sodium phosphate, or thyrocalcitonin resulted in increases in the uptake of AIB by the parathyroids. Large increases in serum magnesium or strontium concentration also suppressed parathyroid AIB uptake. Administration of EDTA to decrease serum calcium concentration resulted in variable effect on parathyroid AIB uptake. This study provides further direct evidence for a negative feedback control of parathyroid function by serum calcium concentration.</description><issn>0037-9727</issn><issn>1535-3702</issn><issn>1535-3699</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1966</creationdate><recordtype>article</recordtype><recordid>eNp9kMFOwzAQRC0EEqXwA5x8hIPbrJ1042OoClQqAiF6jpzUpi5tXNlupfw9CYUrp9WsZlY7j5BbSEYCchgniUCJHBlwzgQApGdkAJnImJhIeU4GvYH1jktyFcImSSBDPhkQXdSHqOnMGF1H6gx90VFt6dw1gbqGLvdRfel-X2z3a8WKnW2cDa46xNbbmha1XdG7Yv5wT6uWvqtI35RXcd16Z1eB2oYe7dGNrsmFUdugb37nkCwfZx_TZ7Z4fZpPiwWreZ5FlmKSG0TMuy4rBKMApMkkF7nIESaVkMZAp9M0Q9C8ay5XdYpYmZQjSimGhJ_u1t6F4LUp997ulG9LSMoeVPkHquxAlT-gutD4FArqU5cbd_BN9-N_iW-NF2YG</recordid><startdate>196605</startdate><enddate>196605</enddate><creator>Au, William Y. W.</creator><creator>Engerman, Judith R.</creator><creator>Risz, Lawrence G.</creator><general>SAGE Publications</general><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>196605</creationdate><title>Acute Effect of Metal Ions on Uptake of Alpha-Aminoisobutyric Acid (AIB) by Rat Parathyroids in vivo.</title><author>Au, William Y. W. ; Engerman, Judith R. ; Risz, Lawrence G.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c285t-4708f7778797d71fa119f5923838716b39ff159244571e23189dc477bf4277993</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1966</creationdate><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Au, William Y. W.</creatorcontrib><creatorcontrib>Engerman, Judith R.</creatorcontrib><creatorcontrib>Risz, Lawrence G.</creatorcontrib><collection>CrossRef</collection><jtitle>Experimental biology and medicine (Maywood, N.J.)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Au, William Y. W.</au><au>Engerman, Judith R.</au><au>Risz, Lawrence G.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Acute Effect of Metal Ions on Uptake of Alpha-Aminoisobutyric Acid (AIB) by Rat Parathyroids in vivo.</atitle><jtitle>Experimental biology and medicine (Maywood, N.J.)</jtitle><date>1966-05</date><risdate>1966</risdate><volume>122</volume><issue>1</issue><spage>285</spage><epage>290</epage><pages>285-290</pages><issn>0037-9727</issn><issn>1535-3702</issn><eissn>1535-3699</eissn><abstract>Summary Acute increases in serum calcium concentration produced by administration of calcium salts, parathyroid extract or high dosages of dihydrotachysterol generally resulted in a decrease in the uptake of AIB by the rat parathyroids in vivo. Acute decreases in serum calcium concentration produced by administration of sodium oxalate, sodium phosphate, or thyrocalcitonin resulted in increases in the uptake of AIB by the parathyroids. Large increases in serum magnesium or strontium concentration also suppressed parathyroid AIB uptake. Administration of EDTA to decrease serum calcium concentration resulted in variable effect on parathyroid AIB uptake. This study provides further direct evidence for a negative feedback control of parathyroid function by serum calcium concentration.</abstract><cop>London, England</cop><pub>SAGE Publications</pub><doi>10.3181/00379727-122-31114</doi><tpages>6</tpages></addata></record>
fulltext fulltext
identifier ISSN: 0037-9727
ispartof Experimental biology and medicine (Maywood, N.J.), 1966-05, Vol.122 (1), p.285-290
issn 0037-9727
1535-3702
1535-3699
language eng
recordid cdi_sage_journals_10_3181_00379727_122_31114
source Alma/SFX Local Collection
title Acute Effect of Metal Ions on Uptake of Alpha-Aminoisobutyric Acid (AIB) by Rat Parathyroids in vivo.
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-02T09%3A12%3A25IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-sage_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Acute%20Effect%20of%20Metal%20Ions%20on%20Uptake%20of%20Alpha-Aminoisobutyric%20Acid%20(AIB)%20by%20Rat%20Parathyroids%20in%20vivo.&rft.jtitle=Experimental%20biology%20and%20medicine%20(Maywood,%20N.J.)&rft.au=Au,%20William%20Y.%20W.&rft.date=1966-05&rft.volume=122&rft.issue=1&rft.spage=285&rft.epage=290&rft.pages=285-290&rft.issn=0037-9727&rft.eissn=1535-3699&rft_id=info:doi/10.3181/00379727-122-31114&rft_dat=%3Csage_cross%3E10.3181_00379727-122-31114%3C/sage_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rft_sage_id=10.3181_00379727-122-31114&rfr_iscdi=true