Modulation of fetal hemoglobin in hereditary persistence of fetal hemoglobin deletion type-2, compared to Sicilian δβ-thalassemia, by BCL11A and SOX6-targeting microRNAs

Hereditary persistence of fetal hemoglobin deletion type-2 (HPFH-2) and Sicilian-δβ-thalassemia are conditions described as large deletions of the human β-like globin cluster, with absent β-globin chains and a compensatory variable increase in γ-globin. HPFH, in general, may be distinguished from DB...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Experimental biology and medicine (Maywood, N.J.) N.J.), 2017-02, Vol.242 (3), p.267-274
Hauptverfasser:	Fornari, Thais A, Lanaro, Carolina, Albuquerque, Dulcinéia M, Ferreira, Regiane, Costa, Fernando F
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!