Factors Modifying Contrast Media Induced Fibrillation
Factors effecting contrast media induced ventricular fibrillation were studied in anesthetized dogs using contact time as the measured parameter. Injections of meglumine/sodium diatrizoate (370 mg I/ml) were made into the right coronary artery at 0.4 ml/s until fibrillation occurred. A contrast medi...
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Veröffentlicht in: | Acta Radiologica. Diagnosis 1985-11, Vol.26 (6), p.771-775 |
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creator | Morris, T. W. Ciaravino, V. Sahler, L. G. Cioffi, B. |
description | Factors effecting contrast media induced ventricular fibrillation were studied in anesthetized dogs using contact time as the measured parameter. Injections of meglumine/sodium diatrizoate (370 mg I/ml) were made into the right coronary artery at 0.4 ml/s until fibrillation occurred. A contrast medium containing calcium chelators was found to produce fibrillation in a significantly shorter contact time than a similar medium without calcium chelators. Pre-treatment by the cardiac glycoside, ouabain, increased the contact time for fibrillation as did the production of a sub-acute infarction in the left coronary artery and a previous fibrillation and resuscitation. The data suggest that calcium binding additives increase the risk of fibrillation while pre-treatment with cardiac glycosides, the presence of stable infarcts in the non-injected areas, or a previous fibrillation and resuscitation do not increase risk. |
doi_str_mv | 10.1177/028418518502600625 |
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The data suggest that calcium binding additives increase the risk of fibrillation while pre-treatment with cardiac glycosides, the presence of stable infarcts in the non-injected areas, or a previous fibrillation and resuscitation do not increase risk.</description><identifier>ISSN: 0567-8056</identifier><identifier>EISSN: 1600-0455</identifier><identifier>DOI: 10.1177/028418518502600625</identifier><identifier>PMID: 4083072</identifier><language>eng</language><publisher>London, England: SAGE Publications</publisher><subject>Animals ; Biological and medical sciences ; Calcium - metabolism ; Chelating Agents - therapeutic use ; Contrast Media - administration & dosage ; Contrast Media - adverse effects ; Contrast media. Radiopharmaceuticals ; Diatrizoate - adverse effects ; Diatrizoate Meglumine - adverse effects ; Dogs ; Drug Combinations - adverse effects ; Medical sciences ; Myocardial Infarction - chemically induced ; Ouabain - therapeutic use ; Pharmacology. Drug treatments ; Risk ; Time Factors ; Ventricular Fibrillation - chemically induced</subject><ispartof>Acta Radiologica. Diagnosis, 1985-11, Vol.26 (6), p.771-775</ispartof><rights>1985 The Foundation Acta Radiologica</rights><rights>1986 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c367t-e2484410ffe0a4a40b4a00c93fb076b793ac2cb98c05992da03c663f477e8e893</citedby><cites>FETCH-LOGICAL-c367t-e2484410ffe0a4a40b4a00c93fb076b793ac2cb98c05992da03c663f477e8e893</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>313,780,784,792,27922,27925</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=8733352$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/4083072$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Morris, T. W.</creatorcontrib><creatorcontrib>Ciaravino, V.</creatorcontrib><creatorcontrib>Sahler, L. G.</creatorcontrib><creatorcontrib>Cioffi, B.</creatorcontrib><title>Factors Modifying Contrast Media Induced Fibrillation</title><title>Acta Radiologica. Diagnosis</title><addtitle>Acta Radiol Diagn (Stockh)</addtitle><description>Factors effecting contrast media induced ventricular fibrillation were studied in anesthetized dogs using contact time as the measured parameter. Injections of meglumine/sodium diatrizoate (370 mg I/ml) were made into the right coronary artery at 0.4 ml/s until fibrillation occurred. A contrast medium containing calcium chelators was found to produce fibrillation in a significantly shorter contact time than a similar medium without calcium chelators. Pre-treatment by the cardiac glycoside, ouabain, increased the contact time for fibrillation as did the production of a sub-acute infarction in the left coronary artery and a previous fibrillation and resuscitation. The data suggest that calcium binding additives increase the risk of fibrillation while pre-treatment with cardiac glycosides, the presence of stable infarcts in the non-injected areas, or a previous fibrillation and resuscitation do not increase risk.</description><subject>Animals</subject><subject>Biological and medical sciences</subject><subject>Calcium - metabolism</subject><subject>Chelating Agents - therapeutic use</subject><subject>Contrast Media - administration & dosage</subject><subject>Contrast Media - adverse effects</subject><subject>Contrast media. Radiopharmaceuticals</subject><subject>Diatrizoate - adverse effects</subject><subject>Diatrizoate Meglumine - adverse effects</subject><subject>Dogs</subject><subject>Drug Combinations - adverse effects</subject><subject>Medical sciences</subject><subject>Myocardial Infarction - chemically induced</subject><subject>Ouabain - therapeutic use</subject><subject>Pharmacology. Drug treatments</subject><subject>Risk</subject><subject>Time Factors</subject><subject>Ventricular Fibrillation - chemically induced</subject><issn>0567-8056</issn><issn>1600-0455</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1985</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9UE1rwkAQXUqLtbZ_oFDIodfU2e_NsUhtBaWX9hwmm11ZiYnsxoP_vhHFi1AYZgbeezO8R8gzhTdKtZ4CM4IaORQwBaCYvCFjOmw5CClvyRik0rkZ-j15SGkDQJmWdERGAgwHzcZEztH2XUzZqquDP4R2nc26to-Y-mzl6oDZoq331tXZPFQxNA32oWsfyZ3HJrmn85yQ3_nHz-wrX35_Lmbvy9xypfvcMWGEoOC9AxQooBIIYAvuK9Cq0gVHy2xVGAuyKFiNwK1S3AutnXGm4BPCTndt7FKKzpe7GLYYDyWF8hhBeR3BIHo5iXb7auvqi-TsecBfzzgmi42P2NqQLjSjOefySJueaAnXrtx0-9gOVv97_AfMCW8H</recordid><startdate>198511</startdate><enddate>198511</enddate><creator>Morris, T. W.</creator><creator>Ciaravino, V.</creator><creator>Sahler, L. G.</creator><creator>Cioffi, B.</creator><general>SAGE Publications</general><general>s.n.</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>198511</creationdate><title>Factors Modifying Contrast Media Induced Fibrillation</title><author>Morris, T. W. ; Ciaravino, V. ; Sahler, L. G. ; Cioffi, B.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c367t-e2484410ffe0a4a40b4a00c93fb076b793ac2cb98c05992da03c663f477e8e893</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1985</creationdate><topic>Animals</topic><topic>Biological and medical sciences</topic><topic>Calcium - metabolism</topic><topic>Chelating Agents - therapeutic use</topic><topic>Contrast Media - administration & dosage</topic><topic>Contrast Media - adverse effects</topic><topic>Contrast media. Radiopharmaceuticals</topic><topic>Diatrizoate - adverse effects</topic><topic>Diatrizoate Meglumine - adverse effects</topic><topic>Dogs</topic><topic>Drug Combinations - adverse effects</topic><topic>Medical sciences</topic><topic>Myocardial Infarction - chemically induced</topic><topic>Ouabain - therapeutic use</topic><topic>Pharmacology. Drug treatments</topic><topic>Risk</topic><topic>Time Factors</topic><topic>Ventricular Fibrillation - chemically induced</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Morris, T. W.</creatorcontrib><creatorcontrib>Ciaravino, V.</creatorcontrib><creatorcontrib>Sahler, L. G.</creatorcontrib><creatorcontrib>Cioffi, B.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><jtitle>Acta Radiologica. Diagnosis</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Morris, T. W.</au><au>Ciaravino, V.</au><au>Sahler, L. G.</au><au>Cioffi, B.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Factors Modifying Contrast Media Induced Fibrillation</atitle><jtitle>Acta Radiologica. Diagnosis</jtitle><addtitle>Acta Radiol Diagn (Stockh)</addtitle><date>1985-11</date><risdate>1985</risdate><volume>26</volume><issue>6</issue><spage>771</spage><epage>775</epage><pages>771-775</pages><issn>0567-8056</issn><eissn>1600-0455</eissn><abstract>Factors effecting contrast media induced ventricular fibrillation were studied in anesthetized dogs using contact time as the measured parameter. Injections of meglumine/sodium diatrizoate (370 mg I/ml) were made into the right coronary artery at 0.4 ml/s until fibrillation occurred. A contrast medium containing calcium chelators was found to produce fibrillation in a significantly shorter contact time than a similar medium without calcium chelators. Pre-treatment by the cardiac glycoside, ouabain, increased the contact time for fibrillation as did the production of a sub-acute infarction in the left coronary artery and a previous fibrillation and resuscitation. The data suggest that calcium binding additives increase the risk of fibrillation while pre-treatment with cardiac glycosides, the presence of stable infarcts in the non-injected areas, or a previous fibrillation and resuscitation do not increase risk.</abstract><cop>London, England</cop><pub>SAGE Publications</pub><pmid>4083072</pmid><doi>10.1177/028418518502600625</doi><tpages>5</tpages></addata></record> |
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subjects | Animals Biological and medical sciences Calcium - metabolism Chelating Agents - therapeutic use Contrast Media - administration & dosage Contrast Media - adverse effects Contrast media. Radiopharmaceuticals Diatrizoate - adverse effects Diatrizoate Meglumine - adverse effects Dogs Drug Combinations - adverse effects Medical sciences Myocardial Infarction - chemically induced Ouabain - therapeutic use Pharmacology. Drug treatments Risk Time Factors Ventricular Fibrillation - chemically induced |
title | Factors Modifying Contrast Media Induced Fibrillation |
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