In vitro investigation of the antimicrobial activity of a series of lipophilic phenols and naphthols : research article
Five groups of phenols/naphthols (42 compounds in total) were synthesized and screened against Gram-positive Staphylococcus aureus and Bacillus subtilis, Gram-negative Escherichia coli and Klebsiella pneumonia, and the fungus Candida albicans. Whereas compounds were found inactive against Gram-negat...
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| Veröffentlicht in: | South African journal of chemistry 2016-01, Vol.69 (1), p.44-50 |
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| container_title | South African journal of chemistry |
| container_volume | 69 |
| creator | Govinden, Usha Mlinaric-Majerski, Kata Bobinac, Damir Zabcic, Ivana Veljkovic, Jelena Mocktar, Chunderik Cindro, Nikola Kruger, Hendrik G. Govender, Thavendran Basaric, Nikola |
| description | Five groups of phenols/naphthols (42 compounds in total) were synthesized and screened against Gram-positive Staphylococcus aureus and Bacillus subtilis, Gram-negative Escherichia coli and Klebsiella pneumonia, and the fungus Candida albicans. Whereas compounds were found inactive against Gram-negative bacteria, potent activities against Gram-positive bacteria were observed. The activities correlate with the ability of molecules to form quinone methides, suggesting potential new modes of action. |
| doi_str_mv | 10.17159/0379-4350/2016/v69a6 |
| format | Article |
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| identifier | ISSN: 0379-4350 |
| ispartof | South African journal of chemistry, 2016-01, Vol.69 (1), p.44-50 |
| issn | 0379-4350 |
| language | eng |
| recordid | cdi_sabinet_saepub_10520_EJC185173 |
| source | DOAJ Directory of Open Access Journals; African Journals Online (Open Access); Sabinet African Journals Open Access Collection; EZB-FREE-00999 freely available EZB journals; Free Full-Text Journals in Chemistry |
| subjects | Antimicrobial activity Naphthols Phenols Quinone methides |
| title | In vitro investigation of the antimicrobial activity of a series of lipophilic phenols and naphthols : research article |
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