Nucleic acid-binding bis-acridine orange dyes with improved properties for bioimaging and PCR applications

Understanding the intricate interactions of molecular dyes with nucleic acids is pivotal for advancing medical and biochemical applications. In this work, we present a comprehensive study of the interplay between a novel series of bis-acridine orange ( BAO ) dyes and double-stranded DNA (dsDNA). The...

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Veröffentlicht in:	Journal of materials chemistry. B, Materials for biology and medicine Materials for biology and medicine, 2024-11, Vol.12 (46), p.11968-11982
Hauptverfasser:	Kulyk, Olesia, Krivoshey, Alexander, Kolosova, Olga, Prylutska, Ivanna, Vasiliu, Tudor, Puf, Razvan, Mocci, Francesca, Laaksonen, Aatto, Perepelytsya, Sergiy, Kobzev, Dmytro, Svoiakov, Rostyslav, Tkachuk, Zenoviy, Tatarets, Anatoliy
Format:	Artikel
Sprache:	eng
Schlagworte:	Acridine orange Acridine Orange - chemistry Binding Comparative analysis Conformation Deoxyribonucleic acid DNA DNA - chemistry Dyes Energiteknik Energy Engineering Fluorescent Dyes - chemical synthesis Fluorescent Dyes - chemistry Humans Medical imaging Medical innovations Medical research Molecular dynamics Molecular Dynamics Simulation Molecular Structure Nucleic acids Polymerase Chain Reaction
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