ADME profiling, molecular docking, DFT, and MEP analysis reveal cissamaline, cissamanine, and cissamdine from L.f. as potential anti-Alzheimer's agents

The current pharmacotherapies for Alzheimer's disease (AD) demonstrate limited efficacy and are associated with various side effects, highlighting the need for novel therapeutic agents. Natural products, particularly from medicinal plants, have emerged as a significant source of potential neuro...

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Veröffentlicht in:RSC advances 2024-03, Vol.14 (14), p.9878-9891
Hauptverfasser: Alhawarri, Maram B, Al-Thiabat, Mohammad G, Dubey, Amit, Tufail, Aisha, Fouad, Dania, Alrimawi, Bilal Harieth, Dayoob, Mohamad
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