Strategic design and development of a siderophore mimic: pioneering anticancer therapy ROS generation and ferroptosis

We designed a tris-catecholate-based siderophore mimic, H 6 - T-CATL , to selectively chelate iron( iii ) from mitochondrial cytochromes and other iron-containing proteins within cellular matrices. This strategic sequestration aims to trigger apoptosis or ferroptosis in cancer cells through the glut...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Dalton transactions : an international journal of inorganic chemistry 2024-07, Vol.53 (29), p.12119-12127
Hauptverfasser: Panwar, Abhishek, Lye, Anushree, Musib, Dulal, Upadhyay, Aarti, Karankumar, Irungbam, Devi, Paonam Bebika, Pal, Maynak, Maity, Biswanath, Roy, Mithun
Format: Artikel
Sprache:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!