Operator-free HPLC automated method development guided by Bayesian optimization

The need to efficiently develop high performance liquid chromatography (HPLC) methods, whilst adhering to quality by design principles is of paramount importance when it comes to impurity detection in the synthesis of active pharmaceutical ingredients. This study highlights a novel approach that ful...

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Veröffentlicht in:	Digital discovery 2024-08, Vol.3 (8), p.1591-161
Hauptverfasser:	Dixon, Thomas M, Williams, Jeanine, Besenhard, Maximilian, Howard, Roger M, MacGregor, James, Peach, Philip, Clayton, Adam D, Warren, Nicholas J, Bourne, Richard A
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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