Insight into the K channel's selectivity from binding of K, Na and water to -methylacetamide

In potassium channels that conduct K + selectively over Na + , which sites are occupied by K + or water and the mechanism of selectivity are unresolved questions. The combination of the energetics and the constraints imposed by the protein structure yield the selective permeation and occupancy. To g...

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Veröffentlicht in:Faraday discussions 2024-01, Vol.249, p.195-29
Hauptverfasser: Stevens, Mark J, Rempe, Susan L. B
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