Synthesis and biological evaluation of -alkyl sulfonamides derived from polycyclic hydrocarbon scaffolds using a nitrogen-centered radical approach

Polycyclic hydrocarbons (PH) provide intriguing potential as lipophilic scaffolds within medicinal chemistry, but are currently limited by the availability of synthetic tools for predictable modification of the PH unit. Herein we report the development of new methods for installation of a sulfonamid...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Organic & biomolecular chemistry 2022-08, Vol.2 (33), p.668-6693
Hauptverfasser:	Hopkins, Megan D, Witt, Ryan C, Flusche, Ann Marie E, Philo, John E, Ozmer, Garett L, Purser, Gordon H, Sheaff, Robert J, Lamar, Angus A
Format:	Artikel
Sprache:
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!