Synthesis and antiproliferative activity of 1-1,2,3-triazole-4-chromene--glucose hybrid compounds with dual inhibitory activity against EGFR/VEGFR-2 and molecular docking studies

A series of 1 H -1,2,3-triazole-4 H -chromene- d -glucose hybrid compounds 7a-o was synthesized via click chemistry using 2-amino-7-propargyloxy-4 H -chromene-3-carbonitriles 5a-o and peracetylated d -glucopyranosyl azide, respectively. CuNP@montmorillonite K10 was used as the catalyst in the presen...

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Veröffentlicht in:New journal of chemistry 2022-12, Vol.46 (48), p.23179-23197
Hauptverfasser: Nguyen, Dinh Thanh, Do, Son Hai, Le, Thi Huyen, Nguyen, Thi Hanh, Nguyen, Minh Huyen, Vu, Thi Ngoc Bich, Pham, Thi Thu Hien, Vu, Ngoc Toan, Hoàng, Thi Kim Van, Nguyen, Thi Kim Giang
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