Mechanistic insights into the mitigation of Aβ aggregation and protofibril destabilization by a -enantiomeric decapeptide rk10

According to clinical studies, the development of Alzheimer's disease (AD) is linked to the abnormal aggregation of amyloid-β (Aβ) peptides into toxic soluble oligomers, protofibrils as well as mature fibrils. The most acceptable therapeutic strategy for the treatment of AD is to block the Aβ a...

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Veröffentlicht in:	Physical chemistry chemical physics : PCCP 2022-09, Vol.24 (36), p.21975-21994
Hauptverfasser:	Singh, Kamaljot, Kaur, Anupamjeet, Goyal, Deepti, Goyal, Bhupesh
Format:	Artikel
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