Pharmaceutical cocrystals of nomegestrol acetate with superior dissolution

The improvement of solubility and dissolution properties are the focus of research on poorly water-soluble APIs. Cocrystallization, which offers a different approach to modify properties of APIs, has gained considerable interest recently. Herein, we designed and synthesized two novel nomegestrol ace...

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Veröffentlicht in:	CrystEngComm 2022-09, Vol.24 (36), p.6385-6391
Hauptverfasser:	Chen, Xiaofeng, Ning, Lifeng
Format:	Artikel
Sprache:	eng
Schlagworte:	Cocrystallization Deionization Dihydroxybenzoic acid Dissolution Fourier transforms Infrared spectroscopy Single crystals Solubility
Online-Zugang:	Volltext
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