Photoredox/copper cocatalyzed domino cyclization of oxime esters with TMSCN: access to antifungal active tetrasubstituted pyrazines

A photoredox/copper cocatalyzed domino cyclization of oxime esters with TMSCN has been developed. A range of structurally novel tetrasubstituted pyrazines have been obtained. This method features high bond-forming efficiency, high step economy, broad substrate scope, and gram-scale synthesis. Moreov...

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Veröffentlicht in:	Chemical communications (Cambridge, England) England), 2022-06, Vol.58 (51), p.72-723
Hauptverfasser:	Cao, Shujun, Yuan, Weidong, Li, Yun, Teng, Xinjie, Si, Huaxing, Chen, Rongshun, Zhu, Yingguang
Format:	Artikel
Sprache:	eng
Schlagworte:	Copper Esters Fungicides Pyrazines Substrates
Online-Zugang:	Volltext
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