Rapid and column-free syntheses of acyl fluorides and peptides using generated thionyl fluoride
Thionyl fluoride (SOF 2 ) was first isolated in 1896, but there have been less than 10 subsequent reports of its use as a reagent for organic synthesis. This is partly due to a lack of facile, lab-scale methods for its generation. Herein we report a novel protocol for the ex situ generation of SOF 2...
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Veröffentlicht in: | Chemical science (Cambridge) 2021-12, Vol.13 (1), p.188-194 |
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