Rapid and column-free syntheses of acyl fluorides and peptides using generated thionyl fluoride

Thionyl fluoride (SOF 2 ) was first isolated in 1896, but there have been less than 10 subsequent reports of its use as a reagent for organic synthesis. This is partly due to a lack of facile, lab-scale methods for its generation. Herein we report a novel protocol for the ex situ generation of SOF 2...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Chemical science (Cambridge) 2021-12, Vol.13 (1), p.188-194
Hauptverfasser: Lee, Cayo, Thomson, Brodie J, Sammis, Glenn M
Format: Artikel
Sprache:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!