Ruthenium-catalyzed -alkylation of amino-1,3,5-triazines using alcohols

An efficient ruthenium-catalyzed N -alkylation of amino 1,3,5-triazines with alcohols was achieved via a BH/HA strategy. Following this simple, facile, and high atom economical protocol, a broad range of products was prepared in moderate to good yields and heterocyclic or benzylic alcohols containing various functionalities were tolerated. The application of the reaction is also further demonstrated by the synthesis of alkylated secondary amine-1,3,5-triazines from olefinated amino-1,3,5-triazines and alcohols via a one pot N -alkylation and reductive reactions. An efficient ruthenium-catalyzed N -alkylation of amino-1,3,5-triazines with alcohols was achieved via BH/HA strategy.