Threonine upregulates the expression of β-defensins by activating the NF-κB signaling pathway and suppressing SIRT1 expression in porcine intestinal epithelial cells

The use of antimicrobial peptide (AMP), found in all forms of life and playing a pivotal role in the innate immune system, has been developed as a new strategy for maintaining intestinal health and reducing antibiotic usage due to its ability to resist pathogens and commensal microbes. The current s...

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Veröffentlicht in:Food & function 2021-07, Vol.12 (13), p.5821-5836
Hauptverfasser: Wang, Chenxi, Yang, Yang, Gao, Nan, Lan, Jing, Dou, Xiujing, Li, Jianping, Shan, Anshan
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