New insight into improving the solubility of poorly soluble drugs by preventing the formation of their hydrogen-bonds: a case of dapsone salts with camphorsulfonic and 5-sulfosalicylic acid

Improving the solubility of poorly soluble drugs has always been a challenging subject in the field of medicine. In this regard, a pharmaceutical cocrystal strategy has been considered to be an effective way. Dapsone (DAP) is nowadays a first-line drug for the treatment of leprosy and is also effect...

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