Oxidation of the inert sp C-H bonds of tetrahydroisoquinolines through C-H activation relay (): construction of functionalized isoquinolin-1-ones

A TBN/O 2 -initiated oxidation of the relatively inert 3,4-C-H bonds of THIQs was accomplished, in which the existence of an α-phosphoric ester group is crucial to enable dioxygen trapping and intramolecular HAT (C-H activation relay, CHAR ), realizing the synthesis of a series of isoquinolin-1-ones...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Chemical communications (Cambridge, England) England), 2021-04, Vol.57 (27), p.3347-335
Hauptverfasser:	Yuan, Yuan, Zhang, Shuwei, Sun, Zheng, Su, Yichun, Ma, Qiyuan, Yuan, Yu, Jia, Xiaodong
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!