Asymmetric synthesis of γ-chiral borylalkanes sequential reduction/hydroboration using a single copper catalyst

The synthesis of γ-chiral borylalkanes through copper-catalyzed enantioselective S N 2′-reduction of γ,γ-disubstituted allylic substrates and subsequent hydroboration was reported. A copper-DTBM-Segphos catalyst produced a range of γ-chiral alkylboronates from easily accessible allylic acetate or be...

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Veröffentlicht in:	Chemical science (Cambridge) 2020-08, Vol.11 (33), p.8961-8965
Hauptverfasser:	Han, Jung Tae, Lee, Jin Yong, Yun, Jaesook
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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