Accelerated trypsin autolysis by affinity polymer templates

Self-cleavage of proteins is an important natural process that is difficult to control externally. Recently a new mechanism for the accelerated autolysis of trypsin was discovered involving polyanionic template polymers; however it relies on unspecific interactions and is inactive at elevated salt l...

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Veröffentlicht in:	RSC advances 2020-08, Vol.1 (48), p.28711-28719
Hauptverfasser:	Smolin, Daniel, Tötsch, Niklas, Grad, Jean-Noël, Linders, Jürgen, Kaschani, Farnusch, Kaiser, Markus, Kirsch, Michael, Hoffmann, Daniel, Schrader, Thomas
Format:	Artikel
Sprache:	eng
Schlagworte:	Affinity Chemistry Computer simulation Copolymers Extreme values Filtration Fluorescence Gel filtration NMR Nuclear magnetic resonance Polymers Spectrometry Trypsin inhibitors
Online-Zugang:	Volltext
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