Synthesis of unsymmetrical urea derivatives one-pot sequential three-component reactions of cyclic 2-diazo-1,3-diketones, carbodiimides, and 1,2-dihaloethanes

A novel and efficient multicomponent reaction of cyclic 2-diazo-1,3-diketones, carbodiimides, and 1,2-dihaloethanes has been developed, and it leads to unsymmetrical urea derivatives with good yields in a single operation. This transformation involves the cascade formation of C-X (X = Cl, Br, I), C-...

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Veröffentlicht in:Organic & biomolecular chemistry 2020-06, Vol.18 (22), p.4178-4182
Hauptverfasser: He, Xinwei, Yang, Cheng, Wu, Yinsong, Xie, Mengqing, Li, Ruxue, Duan, Jiahui, Shang, Yongjia
Format: Artikel
Sprache:eng
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