Efficient unified synthesis of diverse bridged polycyclic scaffolds using a complexity-generating 'stitching' annulation approach

Regioselective and stereospecific directed C-H arylation of simple amine substrates, and cyclisation, delivered 30 diverse, three-dimensional scaffolds. The unified approach significantly expanded the range of bridged ring systems that contain both a nitrogen atom and an aromatic ring. Regioselectiv...

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Veröffentlicht in:	Chemical communications (Cambridge, England) England), 2021-01, Vol.57 (5), p.599-62
Hauptverfasser:	Rice, Scott, Cox, Daniel J, Marsden, Stephen P, Nelson, Adam
Format:	Artikel
Sprache:	eng
Schlagworte:	Aromatic compounds Chemical reactions Scaffolds Stitching Substrates
Online-Zugang:	Volltext
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