Selective arylation and alkenylation of monosubstituted arenes using thianthrene -oxide as a transient mediator
Using thianthrene S -oxide (TTSO) as a transient mediator, para -arylation and alkenylation of mono-substituted arenes have been demonstrated via a para -selective thianthrenation/Pd-catalyzed thio-Suzuki-Miyaura coupling sequence under mild conditions. This reaction features a broad substrate scope...
Gespeichert in:
| Veröffentlicht in: | Chemical communications (Cambridge, England) England), 2020-05, Vol.56 (37), p.558-561 |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artikel |
| Sprache: | eng |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 561 |
|---|---|
| container_issue | 37 |
| container_start_page | 558 |
| container_title | Chemical communications (Cambridge, England) |
| container_volume | 56 |
| creator | Chen, Xiao-Yue Nie, Xiao-Xue Wu, Yichen Wang, Peng |
| description | Using thianthrene
S
-oxide (TTSO) as a transient mediator,
para
-arylation and alkenylation of mono-substituted arenes have been demonstrated
via
a
para
-selective thianthrenation/Pd-catalyzed thio-Suzuki-Miyaura coupling sequence under mild conditions. This reaction features a broad substrate scope, and functional group and heterocycle tolerance. The versatility of this approach was further demonstrated by late-stage functionalization of complex bioactive scaffolds, and direct synthesis of some pharmaceuticals, including Tetriprofen, Ibuprofen, Bifonazole, and LJ570.
Using thianthrene
S
-oxide (TTSO) as a transient mediator,
para
-arylation and alkenylation of mono-substituted arenes have been demonstrated
via
a
para
-selective thianthrenation/Pd-catalyzed thio-Suzuki-Miyaura coupling sequence under mild conditions. |
| doi_str_mv | 10.1039/d0cc00641f |
| format | Article |
| fullrecord | <record><control><sourceid>rsc</sourceid><recordid>TN_cdi_rsc_primary_d0cc00641f</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>d0cc00641f</sourcerecordid><originalsourceid>FETCH-rsc_primary_d0cc00641f3</originalsourceid><addsrcrecordid>eNp9j0FLxEAMhQdRcF29eBfiD6jO0HbdPYvi3T14K7GTutE2s0xS0X9vC4q3zeWF94VHnnOXwd8EX25uo29b71dV6I7cIpSrqqir9cvxvNeb4q6s6lN3pvrupwn1euHSM_XUGn8SYP7u0TgJoETA_oPkz0gdDEmSjq9qbKPRxDMJKYzK8ga2YxTbzRYU6YvjlKaAYBlFmcRgoMhoKZ-7kw57pYtfXbqrx4ft_VORtW32mYfpi-a_Rbl014d4s4_zzeGMH99eWPM</addsrcrecordid><sourcetype>Enrichment Source</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype></control><display><type>article</type><title>Selective arylation and alkenylation of monosubstituted arenes using thianthrene -oxide as a transient mediator</title><source>Royal Society Of Chemistry Journals 2008-</source><source>Alma/SFX Local Collection</source><creator>Chen, Xiao-Yue ; Nie, Xiao-Xue ; Wu, Yichen ; Wang, Peng</creator><creatorcontrib>Chen, Xiao-Yue ; Nie, Xiao-Xue ; Wu, Yichen ; Wang, Peng</creatorcontrib><description>Using thianthrene
S
-oxide (TTSO) as a transient mediator,
para
-arylation and alkenylation of mono-substituted arenes have been demonstrated
via
a
para
-selective thianthrenation/Pd-catalyzed thio-Suzuki-Miyaura coupling sequence under mild conditions. This reaction features a broad substrate scope, and functional group and heterocycle tolerance. The versatility of this approach was further demonstrated by late-stage functionalization of complex bioactive scaffolds, and direct synthesis of some pharmaceuticals, including Tetriprofen, Ibuprofen, Bifonazole, and LJ570.
Using thianthrene
S
-oxide (TTSO) as a transient mediator,
para
-arylation and alkenylation of mono-substituted arenes have been demonstrated
via
a
para
-selective thianthrenation/Pd-catalyzed thio-Suzuki-Miyaura coupling sequence under mild conditions.</description><identifier>ISSN: 1359-7345</identifier><identifier>EISSN: 1364-548X</identifier><identifier>DOI: 10.1039/d0cc00641f</identifier><language>eng</language><ispartof>Chemical communications (Cambridge, England), 2020-05, Vol.56 (37), p.558-561</ispartof><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids></links><search><creatorcontrib>Chen, Xiao-Yue</creatorcontrib><creatorcontrib>Nie, Xiao-Xue</creatorcontrib><creatorcontrib>Wu, Yichen</creatorcontrib><creatorcontrib>Wang, Peng</creatorcontrib><title>Selective arylation and alkenylation of monosubstituted arenes using thianthrene -oxide as a transient mediator</title><title>Chemical communications (Cambridge, England)</title><description>Using thianthrene
S
-oxide (TTSO) as a transient mediator,
para
-arylation and alkenylation of mono-substituted arenes have been demonstrated
via
a
para
-selective thianthrenation/Pd-catalyzed thio-Suzuki-Miyaura coupling sequence under mild conditions. This reaction features a broad substrate scope, and functional group and heterocycle tolerance. The versatility of this approach was further demonstrated by late-stage functionalization of complex bioactive scaffolds, and direct synthesis of some pharmaceuticals, including Tetriprofen, Ibuprofen, Bifonazole, and LJ570.
Using thianthrene
S
-oxide (TTSO) as a transient mediator,
para
-arylation and alkenylation of mono-substituted arenes have been demonstrated
via
a
para
-selective thianthrenation/Pd-catalyzed thio-Suzuki-Miyaura coupling sequence under mild conditions.</description><issn>1359-7345</issn><issn>1364-548X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><sourceid/><recordid>eNp9j0FLxEAMhQdRcF29eBfiD6jO0HbdPYvi3T14K7GTutE2s0xS0X9vC4q3zeWF94VHnnOXwd8EX25uo29b71dV6I7cIpSrqqir9cvxvNeb4q6s6lN3pvrupwn1euHSM_XUGn8SYP7u0TgJoETA_oPkz0gdDEmSjq9qbKPRxDMJKYzK8ga2YxTbzRYU6YvjlKaAYBlFmcRgoMhoKZ-7kw57pYtfXbqrx4ft_VORtW32mYfpi-a_Rbl014d4s4_zzeGMH99eWPM</recordid><startdate>20200507</startdate><enddate>20200507</enddate><creator>Chen, Xiao-Yue</creator><creator>Nie, Xiao-Xue</creator><creator>Wu, Yichen</creator><creator>Wang, Peng</creator><scope/></search><sort><creationdate>20200507</creationdate><title>Selective arylation and alkenylation of monosubstituted arenes using thianthrene -oxide as a transient mediator</title><author>Chen, Xiao-Yue ; Nie, Xiao-Xue ; Wu, Yichen ; Wang, Peng</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-rsc_primary_d0cc00641f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><toplevel>online_resources</toplevel><creatorcontrib>Chen, Xiao-Yue</creatorcontrib><creatorcontrib>Nie, Xiao-Xue</creatorcontrib><creatorcontrib>Wu, Yichen</creatorcontrib><creatorcontrib>Wang, Peng</creatorcontrib><jtitle>Chemical communications (Cambridge, England)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Chen, Xiao-Yue</au><au>Nie, Xiao-Xue</au><au>Wu, Yichen</au><au>Wang, Peng</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Selective arylation and alkenylation of monosubstituted arenes using thianthrene -oxide as a transient mediator</atitle><jtitle>Chemical communications (Cambridge, England)</jtitle><date>2020-05-07</date><risdate>2020</risdate><volume>56</volume><issue>37</issue><spage>558</spage><epage>561</epage><pages>558-561</pages><issn>1359-7345</issn><eissn>1364-548X</eissn><abstract>Using thianthrene
S
-oxide (TTSO) as a transient mediator,
para
-arylation and alkenylation of mono-substituted arenes have been demonstrated
via
a
para
-selective thianthrenation/Pd-catalyzed thio-Suzuki-Miyaura coupling sequence under mild conditions. This reaction features a broad substrate scope, and functional group and heterocycle tolerance. The versatility of this approach was further demonstrated by late-stage functionalization of complex bioactive scaffolds, and direct synthesis of some pharmaceuticals, including Tetriprofen, Ibuprofen, Bifonazole, and LJ570.
Using thianthrene
S
-oxide (TTSO) as a transient mediator,
para
-arylation and alkenylation of mono-substituted arenes have been demonstrated
via
a
para
-selective thianthrenation/Pd-catalyzed thio-Suzuki-Miyaura coupling sequence under mild conditions.</abstract><doi>10.1039/d0cc00641f</doi><tpages>4</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1359-7345 |
| ispartof | Chemical communications (Cambridge, England), 2020-05, Vol.56 (37), p.558-561 |
| issn | 1359-7345 1364-548X |
| language | eng |
| recordid | cdi_rsc_primary_d0cc00641f |
| source | Royal Society Of Chemistry Journals 2008-; Alma/SFX Local Collection |
| title | Selective arylation and alkenylation of monosubstituted arenes using thianthrene -oxide as a transient mediator |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-03T08%3A44%3A04IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-rsc&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Selective%20arylation%20and%20alkenylation%20of%20monosubstituted%20arenes%20using%20thianthrene%20-oxide%20as%20a%20transient%20mediator&rft.jtitle=Chemical%20communications%20(Cambridge,%20England)&rft.au=Chen,%20Xiao-Yue&rft.date=2020-05-07&rft.volume=56&rft.issue=37&rft.spage=558&rft.epage=561&rft.pages=558-561&rft.issn=1359-7345&rft.eissn=1364-548X&rft_id=info:doi/10.1039/d0cc00641f&rft_dat=%3Crsc%3Ed0cc00641f%3C/rsc%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |