Two-step tumor-targeting therapy integrating metabolic lipid-engineering with click chemistry

Highly efficient tumor-targeted therapy remains a great challenge due to the complexity and heterogeneity of tumor tissues. Herein, we developed an in vivo two-step tumor-targeting strategy by combining metabolic lipid-engineering with a stain-promoted azide-alkyne 1,3-dipolar cycloaddition (SPAAC)...

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Veröffentlicht in:	Biomaterials science 2020-04, Vol.8 (8), p.2283-2288
Hauptverfasser:	Lu, Guihong, Zuo, Liping, Zhang, Jinfeng, Zhu, Houshun, Zhuang, Wanru, Wei, Wei, Xie, Hai-Yan
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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