Synthesis and evaluation of antimicrobial activity, cytotoxic and pro-apoptotic effects of novel spiro-4-pyran derivatives

A new library of spiropyrans were synthesized via a one-pot four component reaction of cyanoacetohydrazide, ninhydrin, malononitrile and various cyclic CH-acids in EtOH at reflux conditions. The products were isolated and tested in vitro for antibacterial effects on Escherichia coli ( E. coli ) and...

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Veröffentlicht in:	RSC advances 2019-08, Vol.9 (43), p.24843-24851
Hauptverfasser:	Safari, Fatemeh, Hosseini, Hajar, Bayat, Mohammad, Ranjbar, Ashkan
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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