Contactless, programmable acoustofluidic manipulation of objects on water
Contact-free manipulation of small objects ( e.g. , cells, tissues, and droplets) using acoustic waves eliminates physical contact with structures and undesired surface adsorption. Pioneering acoustic-based, contact-free manipulation techniques ( e.g. , acoustic levitation) enable programmable manip...
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| Veröffentlicht in: | Lab on a chip 2019-10, Vol.19 (2), p.3397-344 |
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| creator | Zhang, Peiran Chen, Chuyi Guo, Feng Philippe, Julien Gu, Yuyang Tian, Zhenhua Bachman, Hunter Ren, Liqiang Yang, Shujie Zhong, Zhanwei Huang, Po-Hsun Katsanis, Nicholas Chakrabarty, Krishnendu Huang, Tony Jun |
| description | Contact-free manipulation of small objects (
e.g.
, cells, tissues, and droplets) using acoustic waves eliminates physical contact with structures and undesired surface adsorption. Pioneering acoustic-based, contact-free manipulation techniques (
e.g.
, acoustic levitation) enable programmable manipulation but are limited by evaporation, bulky transducers, and inefficient acoustic coupling in air. Herein, we report an acoustofluidic mechanism for the contactless manipulation of small objects on water. A hollow-square-shaped interdigital transducer (IDT) is fabricated on lithium niobate (LiNbO
3
), immersed in water and used as a sound source to generate acoustic waves and as a micropump to pump fluid in the ±
x
and ±
y
orthogonal directions. As a result, objects which float adjacent to the excited IDT can be pushed unidirectionally (horizontally) in ±
x
and ±
y
following the directed acoustic wave propagation. A fluidic processor was developed by patterning IDT units in a 6-by-6 array. We demonstrate contactless, programmable manipulation on water of oil droplets and zebrafish larvae. This acoustofluidic-based manipulation opens avenues for the contactless, programmable processing of materials and small biosamples.
Immersed interdigital transducer array enables contactless, programmable manipulation floating objects on water
via
acoustofluidics. |
| doi_str_mv | 10.1039/c9lc00465c |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_rsc_p</sourceid><recordid>TN_cdi_rsc_primary_c9lc00465c</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2303019928</sourcerecordid><originalsourceid>FETCH-LOGICAL-c491t-1a060f47f25b7adcf4f0d477b420e0361c909e3491e08a0dfe19a20f7c08ed633</originalsourceid><addsrcrecordid>eNp9kc1P3DAQxa0KVGDbS--gIC4Iddtx7I3tS6Uq4mOllXppz5bj2DQrJw62A-K_x7B0Cxw4zYzeT08z8xD6guEbBiK-a-E0AK0W-gPax5SROWAudra9YHvoIMY1AF7Qin9EewQvgFeU7qNl7YekdHImxq_FGPx1UH2vGmcKpf0Uk7du6tpOF70aunFyKnV-KLwtfLM2OsUiT3cqmfAJ7Vrlovn8XGfoz8X57_pqvvp1uax_ruaaCpzmWEEFljJbLhqmWm2phZYy1tASDJAKawHCkMwa4Apaa7BQJVimgZu2ImSGfmx8x6npTavNkIJycgxdr8K99KqTr5Wh-yuv_a2sBKEUs2xw-mwQ_M1kYpJ9F7VxTg0mXyzLknNGcclpRk_eoGs_hSGfJ0sCJL9WlDxTZxtKBx9jMHa7DAb5mJCsxap-SqjO8NHL9bfov0gycLgBQtRb9X_EWT9-T5dja8kDMQKh3g</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2303019928</pqid></control><display><type>article</type><title>Contactless, programmable acoustofluidic manipulation of objects on water</title><source>Alma/SFX Local Collection</source><source>Royal Society of Chemistry</source><creator>Zhang, Peiran ; Chen, Chuyi ; Guo, Feng ; Philippe, Julien ; Gu, Yuyang ; Tian, Zhenhua ; Bachman, Hunter ; Ren, Liqiang ; Yang, Shujie ; Zhong, Zhanwei ; Huang, Po-Hsun ; Katsanis, Nicholas ; Chakrabarty, Krishnendu ; Huang, Tony Jun</creator><creatorcontrib>Zhang, Peiran ; Chen, Chuyi ; Guo, Feng ; Philippe, Julien ; Gu, Yuyang ; Tian, Zhenhua ; Bachman, Hunter ; Ren, Liqiang ; Yang, Shujie ; Zhong, Zhanwei ; Huang, Po-Hsun ; Katsanis, Nicholas ; Chakrabarty, Krishnendu ; Huang, Tony Jun</creatorcontrib><description>Contact-free manipulation of small objects (
e.g.
, cells, tissues, and droplets) using acoustic waves eliminates physical contact with structures and undesired surface adsorption. Pioneering acoustic-based, contact-free manipulation techniques (
e.g.
, acoustic levitation) enable programmable manipulation but are limited by evaporation, bulky transducers, and inefficient acoustic coupling in air. Herein, we report an acoustofluidic mechanism for the contactless manipulation of small objects on water. A hollow-square-shaped interdigital transducer (IDT) is fabricated on lithium niobate (LiNbO
3
), immersed in water and used as a sound source to generate acoustic waves and as a micropump to pump fluid in the ±
x
and ±
y
orthogonal directions. As a result, objects which float adjacent to the excited IDT can be pushed unidirectionally (horizontally) in ±
x
and ±
y
following the directed acoustic wave propagation. A fluidic processor was developed by patterning IDT units in a 6-by-6 array. We demonstrate contactless, programmable manipulation on water of oil droplets and zebrafish larvae. This acoustofluidic-based manipulation opens avenues for the contactless, programmable processing of materials and small biosamples.
Immersed interdigital transducer array enables contactless, programmable manipulation floating objects on water
via
acoustofluidics.</description><identifier>ISSN: 1473-0197</identifier><identifier>EISSN: 1473-0189</identifier><identifier>DOI: 10.1039/c9lc00465c</identifier><identifier>PMID: 31508644</identifier><language>eng</language><publisher>England: Royal Society of Chemistry</publisher><subject>Acoustic coupling ; Acoustic levitation ; Acoustic propagation ; Acoustic waves ; Acoustics ; Droplets ; Larvae ; Lithium niobates ; Microprocessors ; Sound sources ; Transducers ; Wave propagation ; Zebrafish</subject><ispartof>Lab on a chip, 2019-10, Vol.19 (2), p.3397-344</ispartof><rights>Copyright Royal Society of Chemistry 2019</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c491t-1a060f47f25b7adcf4f0d477b420e0361c909e3491e08a0dfe19a20f7c08ed633</citedby><cites>FETCH-LOGICAL-c491t-1a060f47f25b7adcf4f0d477b420e0361c909e3491e08a0dfe19a20f7c08ed633</cites><orcidid>0000-0003-0863-4609 ; 0000-0003-1906-7259 ; 0000-0001-9103-3235 ; 0000-0003-1205-3313 ; 0000-0002-0946-574X ; 0000-0003-4475-6435</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>230,314,776,780,881,27903,27904</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/31508644$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Zhang, Peiran</creatorcontrib><creatorcontrib>Chen, Chuyi</creatorcontrib><creatorcontrib>Guo, Feng</creatorcontrib><creatorcontrib>Philippe, Julien</creatorcontrib><creatorcontrib>Gu, Yuyang</creatorcontrib><creatorcontrib>Tian, Zhenhua</creatorcontrib><creatorcontrib>Bachman, Hunter</creatorcontrib><creatorcontrib>Ren, Liqiang</creatorcontrib><creatorcontrib>Yang, Shujie</creatorcontrib><creatorcontrib>Zhong, Zhanwei</creatorcontrib><creatorcontrib>Huang, Po-Hsun</creatorcontrib><creatorcontrib>Katsanis, Nicholas</creatorcontrib><creatorcontrib>Chakrabarty, Krishnendu</creatorcontrib><creatorcontrib>Huang, Tony Jun</creatorcontrib><title>Contactless, programmable acoustofluidic manipulation of objects on water</title><title>Lab on a chip</title><addtitle>Lab Chip</addtitle><description>Contact-free manipulation of small objects (
e.g.
, cells, tissues, and droplets) using acoustic waves eliminates physical contact with structures and undesired surface adsorption. Pioneering acoustic-based, contact-free manipulation techniques (
e.g.
, acoustic levitation) enable programmable manipulation but are limited by evaporation, bulky transducers, and inefficient acoustic coupling in air. Herein, we report an acoustofluidic mechanism for the contactless manipulation of small objects on water. A hollow-square-shaped interdigital transducer (IDT) is fabricated on lithium niobate (LiNbO
3
), immersed in water and used as a sound source to generate acoustic waves and as a micropump to pump fluid in the ±
x
and ±
y
orthogonal directions. As a result, objects which float adjacent to the excited IDT can be pushed unidirectionally (horizontally) in ±
x
and ±
y
following the directed acoustic wave propagation. A fluidic processor was developed by patterning IDT units in a 6-by-6 array. We demonstrate contactless, programmable manipulation on water of oil droplets and zebrafish larvae. This acoustofluidic-based manipulation opens avenues for the contactless, programmable processing of materials and small biosamples.
Immersed interdigital transducer array enables contactless, programmable manipulation floating objects on water
via
acoustofluidics.</description><subject>Acoustic coupling</subject><subject>Acoustic levitation</subject><subject>Acoustic propagation</subject><subject>Acoustic waves</subject><subject>Acoustics</subject><subject>Droplets</subject><subject>Larvae</subject><subject>Lithium niobates</subject><subject>Microprocessors</subject><subject>Sound sources</subject><subject>Transducers</subject><subject>Wave propagation</subject><subject>Zebrafish</subject><issn>1473-0197</issn><issn>1473-0189</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><recordid>eNp9kc1P3DAQxa0KVGDbS--gIC4Iddtx7I3tS6Uq4mOllXppz5bj2DQrJw62A-K_x7B0Cxw4zYzeT08z8xD6guEbBiK-a-E0AK0W-gPax5SROWAudra9YHvoIMY1AF7Qin9EewQvgFeU7qNl7YekdHImxq_FGPx1UH2vGmcKpf0Uk7du6tpOF70aunFyKnV-KLwtfLM2OsUiT3cqmfAJ7Vrlovn8XGfoz8X57_pqvvp1uax_ruaaCpzmWEEFljJbLhqmWm2phZYy1tASDJAKawHCkMwa4Apaa7BQJVimgZu2ImSGfmx8x6npTavNkIJycgxdr8K99KqTr5Wh-yuv_a2sBKEUs2xw-mwQ_M1kYpJ9F7VxTg0mXyzLknNGcclpRk_eoGs_hSGfJ0sCJL9WlDxTZxtKBx9jMHa7DAb5mJCsxap-SqjO8NHL9bfov0gycLgBQtRb9X_EWT9-T5dja8kDMQKh3g</recordid><startdate>20191009</startdate><enddate>20191009</enddate><creator>Zhang, Peiran</creator><creator>Chen, Chuyi</creator><creator>Guo, Feng</creator><creator>Philippe, Julien</creator><creator>Gu, Yuyang</creator><creator>Tian, Zhenhua</creator><creator>Bachman, Hunter</creator><creator>Ren, Liqiang</creator><creator>Yang, Shujie</creator><creator>Zhong, Zhanwei</creator><creator>Huang, Po-Hsun</creator><creator>Katsanis, Nicholas</creator><creator>Chakrabarty, Krishnendu</creator><creator>Huang, Tony Jun</creator><general>Royal Society of Chemistry</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7SP</scope><scope>7TB</scope><scope>7U5</scope><scope>8FD</scope><scope>FR3</scope><scope>L7M</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0003-0863-4609</orcidid><orcidid>https://orcid.org/0000-0003-1906-7259</orcidid><orcidid>https://orcid.org/0000-0001-9103-3235</orcidid><orcidid>https://orcid.org/0000-0003-1205-3313</orcidid><orcidid>https://orcid.org/0000-0002-0946-574X</orcidid><orcidid>https://orcid.org/0000-0003-4475-6435</orcidid></search><sort><creationdate>20191009</creationdate><title>Contactless, programmable acoustofluidic manipulation of objects on water</title><author>Zhang, Peiran ; Chen, Chuyi ; Guo, Feng ; Philippe, Julien ; Gu, Yuyang ; Tian, Zhenhua ; Bachman, Hunter ; Ren, Liqiang ; Yang, Shujie ; Zhong, Zhanwei ; Huang, Po-Hsun ; Katsanis, Nicholas ; Chakrabarty, Krishnendu ; Huang, Tony Jun</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c491t-1a060f47f25b7adcf4f0d477b420e0361c909e3491e08a0dfe19a20f7c08ed633</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2019</creationdate><topic>Acoustic coupling</topic><topic>Acoustic levitation</topic><topic>Acoustic propagation</topic><topic>Acoustic waves</topic><topic>Acoustics</topic><topic>Droplets</topic><topic>Larvae</topic><topic>Lithium niobates</topic><topic>Microprocessors</topic><topic>Sound sources</topic><topic>Transducers</topic><topic>Wave propagation</topic><topic>Zebrafish</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Zhang, Peiran</creatorcontrib><creatorcontrib>Chen, Chuyi</creatorcontrib><creatorcontrib>Guo, Feng</creatorcontrib><creatorcontrib>Philippe, Julien</creatorcontrib><creatorcontrib>Gu, Yuyang</creatorcontrib><creatorcontrib>Tian, Zhenhua</creatorcontrib><creatorcontrib>Bachman, Hunter</creatorcontrib><creatorcontrib>Ren, Liqiang</creatorcontrib><creatorcontrib>Yang, Shujie</creatorcontrib><creatorcontrib>Zhong, Zhanwei</creatorcontrib><creatorcontrib>Huang, Po-Hsun</creatorcontrib><creatorcontrib>Katsanis, Nicholas</creatorcontrib><creatorcontrib>Chakrabarty, Krishnendu</creatorcontrib><creatorcontrib>Huang, Tony Jun</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>Electronics & Communications Abstracts</collection><collection>Mechanical & Transportation Engineering Abstracts</collection><collection>Solid State and Superconductivity Abstracts</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>Advanced Technologies Database with Aerospace</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Lab on a chip</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Zhang, Peiran</au><au>Chen, Chuyi</au><au>Guo, Feng</au><au>Philippe, Julien</au><au>Gu, Yuyang</au><au>Tian, Zhenhua</au><au>Bachman, Hunter</au><au>Ren, Liqiang</au><au>Yang, Shujie</au><au>Zhong, Zhanwei</au><au>Huang, Po-Hsun</au><au>Katsanis, Nicholas</au><au>Chakrabarty, Krishnendu</au><au>Huang, Tony Jun</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Contactless, programmable acoustofluidic manipulation of objects on water</atitle><jtitle>Lab on a chip</jtitle><addtitle>Lab Chip</addtitle><date>2019-10-09</date><risdate>2019</risdate><volume>19</volume><issue>2</issue><spage>3397</spage><epage>344</epage><pages>3397-344</pages><issn>1473-0197</issn><eissn>1473-0189</eissn><abstract>Contact-free manipulation of small objects (
e.g.
, cells, tissues, and droplets) using acoustic waves eliminates physical contact with structures and undesired surface adsorption. Pioneering acoustic-based, contact-free manipulation techniques (
e.g.
, acoustic levitation) enable programmable manipulation but are limited by evaporation, bulky transducers, and inefficient acoustic coupling in air. Herein, we report an acoustofluidic mechanism for the contactless manipulation of small objects on water. A hollow-square-shaped interdigital transducer (IDT) is fabricated on lithium niobate (LiNbO
3
), immersed in water and used as a sound source to generate acoustic waves and as a micropump to pump fluid in the ±
x
and ±
y
orthogonal directions. As a result, objects which float adjacent to the excited IDT can be pushed unidirectionally (horizontally) in ±
x
and ±
y
following the directed acoustic wave propagation. A fluidic processor was developed by patterning IDT units in a 6-by-6 array. We demonstrate contactless, programmable manipulation on water of oil droplets and zebrafish larvae. This acoustofluidic-based manipulation opens avenues for the contactless, programmable processing of materials and small biosamples.
Immersed interdigital transducer array enables contactless, programmable manipulation floating objects on water
via
acoustofluidics.</abstract><cop>England</cop><pub>Royal Society of Chemistry</pub><pmid>31508644</pmid><doi>10.1039/c9lc00465c</doi><tpages>8</tpages><orcidid>https://orcid.org/0000-0003-0863-4609</orcidid><orcidid>https://orcid.org/0000-0003-1906-7259</orcidid><orcidid>https://orcid.org/0000-0001-9103-3235</orcidid><orcidid>https://orcid.org/0000-0003-1205-3313</orcidid><orcidid>https://orcid.org/0000-0002-0946-574X</orcidid><orcidid>https://orcid.org/0000-0003-4475-6435</orcidid><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1473-0197 |
| ispartof | Lab on a chip, 2019-10, Vol.19 (2), p.3397-344 |
| issn | 1473-0197 1473-0189 |
| language | eng |
| recordid | cdi_rsc_primary_c9lc00465c |
| source | Alma/SFX Local Collection; Royal Society of Chemistry |
| subjects | Acoustic coupling Acoustic levitation Acoustic propagation Acoustic waves Acoustics Droplets Larvae Lithium niobates Microprocessors Sound sources Transducers Wave propagation Zebrafish |
| title | Contactless, programmable acoustofluidic manipulation of objects on water |
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