Automated serial dilutions for high-dynamic-range assays enabled by fill-level-coupled valving in centrifugal microfluidics

We introduce a new concept for centrifugal microfluidics that enables fully automated serial dilution generation without any additional means besides temperature control. The key feature is time-independent, serial valving of mixing chambers by fill-level-coupled temperature change rate (FLC-TCR) ac...

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Veröffentlicht in:	Lab on a chip 2019-06, Vol.19 (13), p.225-2219
Hauptverfasser:	Juelg, Peter, Specht, Mara, Kipf, Elena, Lehnert, Michael, Eckert, Cornelia, Keller, Mark, Hutzenlaub, Tobias, von Stetten, Felix, Zengerle, Roland, Paust, Nils
Format:	Artikel
Sprache:	eng
Schlagworte:	Automation Dilution Disks Foils Linearity Microfluidics Temperature control Thermal cycling Thermoforming Wetting
Online-Zugang:	Volltext
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