Development of an efficient and sustainable synthesis of 2-(3-methyl-1-1,2,4-triazol-1-yl) acetic acid under continuous-flow conditions

A novel, metal-free process for the challenging synthesis of 2-(3-methyl-1 H -1,2,4-triazol-1-yl) acetic acid is reported, which features an efficient construction of the triazole ring under flow conditions. This continuous, one-pot method is atom economical, highly selective and environmentally ben...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Green chemistry : an international journal and green chemistry resource : GC 2020-06, Vol.22 (12), p.3748-3758
Hauptverfasser:	Tortoioli, Simone, Friedli, Astrid, Prud'homme, Alice, Richard-Bildstein, Sylvia, Kohler, Philipp, Abele, Stefan, Vilé, Gianvito
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetic acid Construction Continuous flow Green chemistry Sustainable development Synthesis Triazoles
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!