Asymmetric Si-rhodamine scaffolds: rational design of pH-durable protease-activated NIR probes

A group of asymmetric Si-rhodamine scaffolds was designed for protease-activated NIR probes. Dual pH-inertia for both spirocyclized fluorescent probes and fluorescent products of zwitterions form over a wide range of pH (4.0-11.0). Leucine aminopeptidase (LAP) and γ-glutamyl transpeptidase (GGT) wer...

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Veröffentlicht in:	Chemical communications (Cambridge, England) England), 2020-02, Vol.56 (16), p.2455-2458
Hauptverfasser:	Li, Min, Wang, Chuanfeng, Wang, Ting, Fan, Mengting, Wang, Ning, Ma, Danying, Hu, Ting, Cui, Xiaoyan
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