Efficient differentiation of human ES and iPS cells into cardiomyocytes on biomaterials under xeno-free conditions

Current xeno-free and chemically defined methods for the differentiation of hPSCs (human pluripotent stem cells) into cardiomyocytes are not efficient and are sometimes not reproducible. Therefore, it is necessary to develop reliable and efficient methods for the differentiation of hPSCs into cardio...

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Veröffentlicht in:	Biomaterials science 2019-11, Vol.7 (12), p.5467-5481
Hauptverfasser:	Sung, Tzu-Cheng, Liu, Cheng-Hui, Huang, Wei-Lun, Lee, Yu-Chun, Kumar, S. Suresh, Chang, Yung, Ling, Qing-Dong, Hsu, Shih-Tien, Higuchi, Akon
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biocompatible Materials - pharmacology Biomedical materials Cardiomyocytes Cell Differentiation - drug effects Cell Line Differentiation Embryonic Stem Cells - cytology Embryonic Stem Cells - drug effects Humans Induced Pluripotent Stem Cells - cytology Induced Pluripotent Stem Cells - drug effects Laminin Myocytes, Cardiac - cytology Myocytes, Cardiac - drug effects Organic chemistry Stem cells
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