An unusual double chain-initiating nonribosomal peptide synthetase assembles 'fungal' icosalide antibiotics

Burkholderia is a multi-talented genus of Gram-negative bacteria, which in recent years has become increasingly recognised as a promising source of bioactive natural products. Metabolite profiling of Burkholderia gladioli BCC0238 showed that it produces the asymmetric lipopeptidiolide antibiotic ico...

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Veröffentlicht in:	Chemical science (Cambridge) 2019-05, Vol.1 (21), p.5489-5494
Hauptverfasser:	Jenner, Matthew, Jian, Xinyun, Dashti, Yousef, Masschelein, Joleen, Hobson, Christian, Roberts, Douglas M, Jones, Cerith, Harris, Simon, Parkhill, Julian, Raja, Huzefa A, Oberlies, Nicholas H, Pearce, Cedric J, Mahenthiralingam, Eshwar, Challis, Gregory L
Format:	Artikel
Sprache:	eng
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