miR-124 and miR-142 enhance cisplatin sensitivity of non-small cell lung cancer cells through repressing autophagy directly targeting SIRT1

Background : Drug resistance is a major obstacle in the treatment of non-small cell lung cancer (NSCLC). Recently, miRNAs are reported to be involved in the drug resistance of NSCLC. The roles of miR-124 and miR-142 in the multidrug resistance of NSCLC cells have been reported. However, the underlyi...

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Veröffentlicht in:RSC advances 2019-02, Vol.9 (9), p.5234-5243
Hauptverfasser: Song, Xiang, Kong, Fanyi, Zong, Zhenfeng, Ren, Mingming, Meng, Qingjun, Li, Yanguang, Sun, Zhen
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