Stabilization of an intermolecular i-motif by lipid modification of cytosine-oligodeoxynucleotidesElectronic supplementary information (ESI) available. See DOI: 10.1039/c8ob00920a
This paper describes the stabilization of an intermolecular i-motif by lipophilic modification on the 3′-terminus of oligonucleotides. The hydrophobic aliphatic chain connected at the 3′-terminus of a trinucleotide (dC) 3 promoted the formation of an i-motif and significantly enhanced the quadruplex...
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