Design and synthesis of (aza)indolyl maleimide-based covalent inhibitors of glycogen synthase kinase 3βElectronic supplementary information (ESI) available. See DOI: 10.1039/c8ob00642c

As an important kinase in multiple signal transduction pathways, GSK-3β has been an attractive target for chemical probe discovery and drug development. Compared to numerous reversible inhibitors that have been developed, covalent inhibitors of GSK-3β are noticeably lacking. Here, we report the disc...

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Hauptverfasser:	Yang, Zhimin, Liu, Hui, Pan, Botao, He, Fengli, Pan, Zhengying
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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